FXYD3 Antibody (YA7829)

Art. -Nr.: HY-P88145: Data Sheet User Guide for Antibodies
FAQs
Technical Support

FXYD3 Antibody (YA7829) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to FXYD3.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Größe	Preis	Verfügbarkeit
20 μL		Anfrage über Preis & Lieferzeit
50 μL		Anfrage über Preis & Lieferzeit
100 μL		Anfrage über Preis & Lieferzeit

* Bitte wählen Sie Menge, bevor Sie Artikel hinzufügen.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Beschreibung

Beschreibung

FXYD3 Antibody (YA7829) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to FXYD3.

Host

Mouse

Clonality

Monoclonal

Molekulargewicht

Predicted band size: 7.1 kDa

Species Reactivity

Human

SwissProt ID

Q14802

Immunogen

Full length human recombinant protein of human FXYD3 produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250
FC FC: Flow Cytometry	1:100

Sensitivity	Endogenous	Reinheit	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG2a

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Versand

Shipping with blue ice.

Background

Function：Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell (PubMed:17077088). Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1 (PubMed:21454534). Induces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes (PubMed:7836447)|Decreases the apparent K+ and Na+ affinity of the sodium/potassium-transporting ATPase over a large range of membrane potentials|Decreases the apparent K+ affinity of the sodium/potassium-transporting ATPase only at slightly negative and positive membrane potentials and increases the apparent Na+ affinity over a large range of membrane potentials

Subcellular Localization：Cell membrane

Expression：
Tissue_Specificity: Isoform 1: Expressed mainly in differentiated cells (at protein level). Isoform 2: Expressed mainly in undifferentiated cells (at protein level)

Isoforms & Post-Translational Modification：Q14802 has 5 isomers: Q14802-1: 9263 Da (predicted); Q14802-2: 11988 Da (predicted); Q14802-3: 15154 Da (predicted); Q14802-4: 10280 Da (predicted); Q14802-5: 6718 Da (predicted).
Glutathionylated

Subunit：Regulatory subunit of the sodium/potassium-transporting ATPase which is composed of a catalytic alpha subunit, a non-catalytic beta subunit and an additional regulatory subunit (PubMed:17077088)

Synonyms

MAT8; PLML

Dokumentation

User Guide for Antibodies (1077 KB)