KATNB1 (Katanin p80) Antibody (YA8468)(PBS only)

Cat. No.: HY-P88784A: Data Sheet User Guide for Antibodies
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KATNB1 (Katanin p80) Antibody (YA8468) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to KATNB1 (Katanin p80).

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

KATNB1 (Katanin p80) Antibody (YA8468) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to KATNB1 (Katanin p80).

Host

Mouse

Molecular Weight

Predicted band size: 72.2 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q9BVA0

Immunogen

Full length human recombinant protein of human KATNB1 produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250
FC FC: Flow Cytometry	1:100

Purity	Affinity purified	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth

Subcellular Localization：Cytoplasm,Cytoplasm, cytoskeleton, microtubule organizing center, centrosome,Cytoplasm, cytoskeleton, spindle pole,Cytoplasm, cytoskeleton,Cytoplasm, cytoskeleton, spindle

Isoforms & Post-Translational Modification：Q9BVA0: 655 amino acids, molecular weight 72334 Da.

Subunit：Interacts with PAFAH1B1 (By similarity)

Synonyms

KAT; LIS6

Documentation

User Guide for Antibodies (1077 KB)