KATNB1 (Katanin p80) Antibody (YA8468)

Art. -Nr.: HY-P88784: Data Sheet User Guide for Antibodies
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KATNB1 (Katanin p80) Antibody (YA8468) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to KATNB1 (Katanin p80).

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100 μL		Angebot einholen

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Beschreibung

Beschreibung

KATNB1 (Katanin p80) Antibody (YA8468) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to KATNB1 (Katanin p80).

Host

Mouse

Clonality

Monoclonal

Molekulargewicht

Predicted band size: 72.2 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q9BVA0

Immunogen

Full length human recombinant protein of human KATNB1 produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250
FC FC: Flow Cytometry	1:100

Sensitivity	Endogenous	Reinheit	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Versand

Shipping with blue ice.

Background

Function：Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth

Subcellular Localization：Cytoplasm,Cytoplasm, cytoskeleton, microtubule organizing center, centrosome,Cytoplasm, cytoskeleton, spindle pole,Cytoplasm, cytoskeleton,Cytoplasm, cytoskeleton, spindle

Isoforms & Post-Translational Modification：Q9BVA0: 655 amino acids, molecular weight 72334 Da.

Subunit：Interacts with PAFAH1B1 (By similarity)

Synonyms

KAT; LIS6

Dokumentation

User Guide for Antibodies (1077 KB)