KCNJ3 (GIRK1 ) Antibody (YA8284)(PBS only)

Cat. No.: HY-P88600A: Data Sheet User Guide for Antibodies
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KCNJ3 (GIRK1 ) Antibody (YA8284) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to KCNJ3 (GIRK1 ).

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

KCNJ3 (GIRK1 ) Antibody (YA8284) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to KCNJ3 (GIRK1 ).

Host

Mouse

Molecular Weight

Predicted band size: 56.4 kDa

Species Reactivity

Human, Monkey, Mouse, Rat

SwissProt ID

P48549

Immunogen

Human recombinant protein fragment corresponding to amino acids 279-501 of human KCNJ3 produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250
FC FC: Flow Cytometry	1:100

Purity	Affinity purified	Conjugation	Non-conjugated
Isotype	IgG2b

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This potassium channel is controlled by G proteins (PubMed:8804710, PubMed:8868049). This receptor plays a crucial role in regulating the heartbeat (By similarity)

Subcellular Localization：Membrane

Isoforms & Post-Translational Modification：P48549 has two isomers: P48549-1: 56603 Da (predicted); P48549-2: 26829 Da (predicted).

Subunit：Associates with KCNJ5/GIRK4 or KCNJ6/GIRK2 to form a G-protein activated heteromultimer pore-forming unit

Synonyms

GIRK1; KGA; KIR3.1

Documentation

User Guide for Antibodies (1077 KB)