KLHL21 Antibody (YA4936)(PBS only)

Cat. No.: HY-P85244A: Data Sheet User Guide for Antibodies
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KLHL21 Antibody (YA4936) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to KLHL21.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

사이즈		재고
50 μL		견적 받기
100 μL		견적 받기

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명

제품 설명

KLHL21 Antibody (YA4936) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to KLHL21.

Host

Mouse

분자량

Predicted band size: 66kDa;

Species Reactivity

Human

SwissProt ID

Q9UJP4

Gene ID

9903 [NCBI]

Immunogen

Purified recombinant fragment of human KLHL21 expressed in E. Coli. The exact sequence is proprietary to MCE.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:200-1:1000
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Purity	affinity purified	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome

Subcellular Localization：Cytoplasm, cytoskeleton, spindle

Isoforms & Post-Translational Modification：Q9UJP4 has 2 isomers: Q9UJP4-1: 66617 Da (predicted); Q9UJP4-2: 60378 Da (predicted).

Subunit：Component of the BCR(KLHL21) E3 ubiquitin ligase complex, at least composed of CUL3, KLHL21 and RBX1

Synonyms

KLHL21; KIAA0469; Kelch-like protein 21

각종 서류

User Guide for Antibodies (1077 KB)