Neprilysin-2/MMEL1 Antibody (YA7059)

Cat. No.: HY-P87376: Data Sheet User Guide for Antibodies
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Neprilysin-2/MMEL1 Antibody (YA7059) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Neprilysin-2/MMEL1.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

사이즈		재고
50 μL		견적 받기
100 μL		견적 받기

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명

제품 설명

Neprilysin-2/MMEL1 Antibody (YA7059) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Neprilysin-2/MMEL1.

Host

Mouse

Clonality

Monoclonal

분자량

Predicted band size: 89.4kDa;

Observed band size: 89.4kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

Q495T6

Immunogen

Purified recombinant fragment of human MMEL1 (AA: 1-107) expressed in E. Coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:200-1:1000
FC FC: Flow Cytometry	1:200-1:400
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Sensitivity	Endogenous	Purity	Protein A affinity purified.
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in in PBS with 0.05% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：Metalloprotease involved in sperm function, possibly by modulating the processes of fertilization and early embryonic development. Degrades a broad variety of small peptides with a preference for peptides shorter than 3 kDa containing neutral bulky aliphatic or aromatic amino acid residues. Shares the same substrate specificity with MME and cleaves peptides at the same amide bond (By similarity)

Subcellular Localization：Membrane,Secreted

Expression：
Tissue_Specificity: Predominantly expressed in testis. Weakly expressed in brain, kidney and heart

Isoforms & Post-Translational Modification：Q495T6 has three isomers: Q495T6-1: 89367 Da (predicted); Q495T6-2: 69930 Da (predicted); Q495T6-3: 71092 Da (predicted).
N-glycosylated

Synonyms

Mel transforming oncogene like 1 antibody; Membrane metallo endopeptidase like 1 antibody; Membrane metallo endopeptidase like 2 antibody; Membrane metallo-endopeptidase-like 1 antibody; Membrane metallo-endopeptidase-like 2 antibody; MMEL1 antibody; MMEL1_HUMAN antibody; NEP2 antibody; NEP2(m) antibody; NEP2(s) antibody

각종 서류

User Guide for Antibodies (1077 KB)