RBM46 Antibody (YA8531)

Cat. No.: HY-P88847: Data Sheet User Guide for Antibodies
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RBM46 Antibody (YA8531) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RBM46.

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사이즈		재고
50 μL		견적 받기
100 μL		견적 받기

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명

제품 설명

RBM46 Antibody (YA8531) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RBM46.

Host

Mouse

Clonality

Monoclonal

분자량

Predicted band size: 59.8 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q8TBY0

Immunogen

Full length human recombinant protein of human RBM46 produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250
FC FC: Flow Cytometry	1:100

Sensitivity	Endogenous	Purity	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：Essential for male and female fertility, playing a crucial role in regulating germ cell development by ensuring the proper progression of meiosis prophase I (By similarity). Regulates mitotic-to-meiotic transition in spermatogenesis by forming a complex with MEIOC and YTHDC2 which recognizes and down-regulates mitotic transcripts for a successful meiotic entry (By similarity). Required for normal synaptonemal complex formation during meiosis, binding meiotic cohesin subunit mRNAs containing GCCUAU/GUUCGA motifs in their 3'UTRs regions and positively regulating their translation (By similarity). Required for spermatogonial differentiation in both developing and adult testis (By similarity)

Subcellular Localization：Cytoplasm

Isoforms & Post-Translational Modification：Q8TBY0 has three isomers: Q8TBY0-1: 60023 Da (predicted); Q8TBY0-2: 53245 Da (predicted); Q8TBY0-3: 55283 Da (predicted).

Subunit：Interacts with YTHDC2, MEIOC, MOV10, CNOT6L, DDX4, UPF1 and PABPC1

Synonyms

CT68

각종 서류

User Guide for Antibodies (1077 KB)