TACC1 Antibody (YA8711)(PBS only)

Cat. No.: HY-P89027A: Data Sheet User Guide for Antibodies
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TACC1 Antibody (YA8711) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TACC1.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

TACC1 Antibody (YA8711) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TACC1.

Host

Mouse

Molecular Weight

Predicted band size: 43.8 kDa

Species Reactivity

Human

SwissProt ID

O75410

Immunogen

Full length human recombinant protein of human TACC1 produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500

Purity	Affinity purified	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Involved in transcription regulation induced by nuclear receptors, including in T3 thyroid hormone and all-trans retinoic acid pathways (PubMed:20078863). Might promote the nuclear localization of the receptors (PubMed:20078863). Likely involved in the processes that promote cell division prior to the formation of differentiated tissues

Subcellular Localization：Cytoplasm,Nucleus,Cytoplasm, cytoskeleton, microtubule organizing center, centrosome,Midbody,Membrane,Cytoplasm

Expression：
Tissue_Specificity: Isoform 1, isoform 3 and isoform 5 are ubiquitous. Isoform 2 is strongly expressed in the brain, weakly detectable in lung and colon, and overexpressed in gastric cancer. Isoform 4 is not detected in normal tissues, but strong expression was found in gastric cancer tissues. Down-regulated in a subset of cases of breast cancer

Isoforms & Post-Translational Modification：O75410 has 10 isomers: O75410-1: 87794 Da (predicted); O75410-2: 89218 Da (predicted); O75410-3: 67073 Da (predicted); O75410-4: 42326 Da (predicted); O75410-5: 40903 Da (predicted); O75410-6: 43984 Da (predicted); O75410-7: 79872 Da (predicted); O75410-8: 17815 Da (predicted); O75410-9: 84624 Da (predicted); O75410-10: 40814 Da (predicted).
Isoform 1 is heavily phosphorylated; isoform 6 is not

Subunit：Interacts with KIAA0097/CH-TOG and with the oncogenic transcription factor YEATS4

Synonyms

Ga55

Documentation

User Guide for Antibodies (1077 KB)