VIP Antibody (YA6836)

(Synonyms: Peptide histidine methioninamide 27 antibody; Peptide histidine valine 42 antibody; PHM27 antibody; PHV42 antibody; Prepro V; IP : antibody; Vasoactive intestinal peptide antibody; Vasoactive intestinal polypeptide antibody; V; IP : antibody; V; IP : peptides antibody; V; IP : peptides precursor antibody; Peptide histidine methioninamide 27 antibody; Peptide histidine valine 42 antibody; PHM27 antibody; PHV42 antibody; Prepro V; IP : antibody; Vasoactive intestinal peptide antibody; Vasoactive intestinal polypeptide antibody; V; IP : antibody; V; IP : peptides antibody; V; IP : peptides precursor antibody; VIP_HUMAN antibody; )

VIP Antibody (YA6836) is a Rat -derived and non-conjugated monoclonal antibody, targeting to VIP.

For research use only. We do not sell to patients.
  • Host:

    Rat

  • Application:

    IHC-F, IHC-P

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

  • Conjugation:
    Non-conjugated

Applications

Application
IHC-F Info
IHC-F: Immunohistochemistry-Frozen
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
Dilution Ratio 1:500 1:1000

Product Details

Description

VIP Antibody (YA6836) is a Rat -derived and non-conjugated monoclonal antibody, targeting to VIP.

  • Host Rat
  • Clonality Recombinant,Monoclonal
  • Species Reactivity
    Human, Mouse, Rat Predicted Reactivity: Cynomolgus monkey
    Info
    Note: The predicted reactivity is for reference only and should not be considered a guarantee of product performance.
  • Calculated Molecular Weight Predicted band size: 19 kDa
Purification

affinity purified.

Conjugation

Non-conjugated

Modification

Unmodified

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Verification Images

  • Experimental Validation Results for VIP Antibody (YA6836)
    Immunohistochemical analysis of paraffin-embedded human appendix tissue using VIP Antibody (YA6836) . The section was pre-treated using heat mediated antigen retrieval with Tris/EDTA buffer (pH 9.0) for 20 minutes. The tissues were probed with the primary antibody (HY-P87143, 1/100) overnight at 4℃. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with neutral balsam.
  • Experimental Validation Results for VIP Antibody (YA6836)
    Immunohistochemical analysis of paraffin-embedded human colon tissue using VIP Antibody (YA6836) . The section was pre-treated using heat mediated antigen retrieval with Tris/EDTA buffer (pH 9.0) for 20 minutes. The tissues were probed with the primary antibody (HY-P87143, 1/100) overnight at 4℃. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with neutral balsam.
  • Experimental Validation Results for VIP Antibody (YA6836)
    Immunohistochemical analysis of paraffin-embedded human brain tissue using VIP Antibody (YA6836) . The section was pre-treated using heat mediated antigen retrieval with Tris/EDTA buffer (pH 9.0) for 20 minutes. The tissues were probed with the primary antibody (HY-P87143, 1/100) overnight at 4℃. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with neutral balsam.
  • Experimental Validation Results for VIP Antibody (YA6836)
    Immunohistochemical analysis of paraffin-embedded human pituitary adenoma tissue using VIP Antibody (YA6836) . The section was pre-treated using heat mediated antigen retrieval with Tris/EDTA buffer (pH 9.0) for 20 minutes. The tissues were probed with the primary antibody (HY-P87143, 1/100) overnight at 4℃. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with neutral balsam.
  • Experimental Validation Results for VIP Antibody (YA6836)
    Immunohistochemical analysis of paraffin-embedded human pituitary adenoma tissue using VIP Antibody (YA6836) . The section was pre-treated using heat mediated antigen retrieval with Tris/EDTA buffer (pH 9.0) for 20 minutes. The tissues were probed with the primary antibody (HY-P87143, 1/100) overnight at 4℃. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with neutral balsam.
  • Experimental Validation Results for VIP Antibody (YA6836)
    Immunohistochemical analysis of paraffin-embedded human esophagus tissue using VIP Antibody (YA6836) . The section was pre-treated using heat mediated antigen retrieval with Tris/EDTA buffer (pH 9.0) for 20 minutes. The tissues were probed with the primary antibody (HY-P87143, 1/100) overnight at 4℃. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with neutral balsam.
  • Experimental Validation Results for VIP Antibody (YA6836)
    Immunohistochemical analysis of paraffin-embedded human esophagus tissue using VIP Antibody (YA6836) . The section was pre-treated using heat mediated antigen retrieval with Tris/EDTA buffer (pH 9.0) for 20 minutes. The tissues were probed with the primary antibody (HY-P87143, 1/100) overnight at 4℃. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with neutral balsam.

Background

  • Function

    VIP is a VIP is a neuropeptide involved in a diverse array of physiological processes through activating the PACAP subfamily of class B1 G protein-coupled receptors: VIP receptor 1 (VPR1) and VIP receptor 2 (VPR2). Abundantly expressed throughout the CNS and peripheral nervous systems where they primarily exert neuroprotective and immune modulatory roles. Also causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder |PHM-27 and PHV-42 are two bioactive forms from proteolysis of the same precursor protein, that cause vasodilation. PHM-27 is a potent agonist of the calcitonin receptor CALCR, with similar efficacy as calcitonin[1][2][3][4][5][6].

  • Subcellular Localization

    Secreted

  • Isoforms & Post-Translational Modification

    P01282 has two isomers: P01282-1: 19169 Da (predicted); P01282-2: 19082 Da (predicted).

  • SwissProt ID

    P01282

  • Gene ID
  • Synonyms

    Peptide histidine methioninamide 27 antibody; Peptide histidine valine 42 antibody; PHM27 antibody; PHV42 antibody; Prepro V; IP : antibody; Vasoactive intestinal peptide antibody; Vasoactive intestinal polypeptide antibody; V; IP : antibody; V; IP : peptides antibody; V; IP : peptides precursor antibody; Peptide histidine methioninamide 27 antibody; Peptide histidine valine 42 antibody; PHM27 antibody; PHV42 antibody; Prepro V; IP : antibody; Vasoactive intestinal peptide antibody; Vasoactive intestinal polypeptide antibody; V; IP : antibody; V; IP : peptides antibody; V; IP : peptides precursor antibody; VIP_HUMAN antibody;

VIP Antibody (YA6836) Related Classifications

MOQ
Minimum order quantity
100 mg

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