von Willebrand Factor Antibody (YA2406)(PBS only)

Cat. No.: HY-P82661A: Data Sheet User Guide for Antibodies
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von Willebrand Factor Antibody (YA2406) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to von Willebrand Factor.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

von Willebrand Factor Antibody (YA2406) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to von Willebrand Factor.

Host

Rabbit

Molecular Weight

Predicted band size: 309 kDa;

Observed band size: 309 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Rat

SwissProt ID

P04275

Gene ID

7450 [NCBI]

Immunogen

A synthetic peptide of human Von Willebrand Factor

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:100

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma

Subcellular Localization：Secreted; Secreted, extracellular space, extracellular matrix

Expression：
Tissue_specificity:plasma

Isoforms & Post-Translational Modification：P04275 has 2 isomers: P04275-1: 309265 Da (predicted); P04275-2: 38745 Da (predicted).
All cysteine residues are involved in intrachain or interchain disulfide bonds;N- and O-glycosylated

Subunit：Multimeric. Interacts with F8

Research Field

Cardiovascular

Synonyms

VWF; von Willebrand factor; von Willebrand antigen II; F8VWF

Documentation

User Guide for Antibodies (1077 KB)