WNT4 Antibody (YA7047)

製品番号: HY-P87364: データシート User Guide for Antibodies
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WNT4 Antibody (YA7047) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to WNT4.

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研究用途以外に使用した場合、当社は一切の責任を負いかねます。

容量		在庫状況
50 μL		お問い合わせ
100 μL		お問い合わせ

* アイテムを追加する前、数量をご選択ください

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明

製品説明

WNT4 Antibody (YA7047) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to WNT4.

Host

Mouse

Clonality

Monoclonal

分子量

Predicted band size: 40 kDa;

Observed band size: 40 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P56705

Immunogen

peptide

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000
IP IP: Immunoprecipitation	1-2 μg per 100-500 μg of total protein
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-500
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-500

Sensitivity	Endogenous	純度	Protein A affinity purified.
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin.

Storage & Stability

Stored at 2-8°C for 1 year, do not freeze.

輸送条件

Shipping with blue ice.

Background

Function：Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Plays an important role in the embryonic development of the urogenital tract and the lung (PubMed:15317892, PubMed:16959810, PubMed:18179883, PubMed:18182450). Required for normal mesenchyme to epithelium transition during embryonic kidney development. Required for the formation of early epithelial renal vesicles during kidney development (By similarity). Required for normal formation of the Mullerian duct in females, and normal levels of oocytes in the ovaries (PubMed:15317892, PubMed:16959810, PubMed:18182450). Required for normal down-regulation of 3 beta-hydroxysteroid dehydrogenase in the ovary (PubMed:15317892, PubMed:16959810, PubMed:18182450). Required for normal lung development and for normal patterning of trachael cartilage rings (By similarity)

Subcellular Localization：Secreted, extracellular space, extracellular matrix

Isoforms & Post-Translational Modification：P56705 has two isomers: P56705-1: 39052 Da (predicted); P56705-2: 32954 Da (predicted).
Palmitoleoylation is required for efficient binding to frizzled receptors

Subunit：Interacts with PORCN (By similarity)

Synonyms

MGC123964 antibody; Protein Wnt-4 antibody; RP23-246F18.1 antibody; SERKAL antibody; Wingless type MMTV integration site family member 4 precursor antibody; WNT 4 antibody; WNT 4 protein precursor antibody; WNT4 antibody; WNT4_HUMAN antibody

ドキュメンテーション

User Guide for Antibodies (1077 KB)

WNT4 Antibody (YA7047) 関連分類

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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WNT4 Antibody (YA7047)

Product Detail

Background

説明

WNT4 Antibody (YA7047) 関連分類

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