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  4. Antiproliferative agent-77

Antiproliferative agent-77 is an anticancer cell proliferation agent that exerts significant antiproliferative effects on HCT116, HepG2, H1299 and MCF-7.

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Antiproliferative agent-77

Antiproliferative agent-77 構造式

CAS 番号 : 1446686-55-0

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Antiproliferative agent-77 関連抗体

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製品説明

Antiproliferative agent-77 is an anticancer cell proliferation agent that exerts significant antiproliferative effects on HCT116, HepG2, H1299 and MCF-7[1].

体外実験

Antiproliferative agent-77 (Positive control L029) (3.125-100 μM; 2 days) potently inhibits the proliferation of HCT116, HepG2, H1299 and MCF-7 cells, with IC50 values of 14.25 μM, 22.05 μM, 13.69 μM and 28.21 μM, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Antiproliferative agent-77 関連抗体

Cell Proliferation Assay[1]

Cell Line: HCT116 (human colon cancer), HepG2 (human liver cancer), H1299 (human lung adenocarcinoma), MCF-7 (human breast cancer)
Concentration: 3.125, 6.25, 12.5, 25, 50 and 100 μM
Incubation Time: 2 days (drug incubation); 1 day (pre-culture); 2 hours (MTS incubation)
Result: Potently inhibited proliferation of HCT116 cells with an IC50 of 14.25 μM.
Potently inhibited proliferation of HepG2 cells with an IC50 of 22.05 μM.
Potently inhibited proliferation of H1299 cells with an IC50 of 13.69 μM.
Potently inhibited proliferation of MCF-7 cells with an IC50 of 28.21 μM.
分子量

430.48

分子式

C23H18N4O3S
CAS 番号
SMILES

O=C1NC2=CC=C(S(=O)(NC3=C(C)C=CC=C3)=O)C=C2/C1=C/C4=NC5=C(N4)C=CC=C5
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.
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Antiproliferative agent-77 Related Classifications

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Keywords:

Antiproliferative agent-771446686-55-0Antiproliferative agent77Antiproliferative agent 77Othershuman lung adenocarcinomaHCT116human colon cancerHepG2MCF-7human liver cancerH1299human breast cancerInhibitorinhibitorinhibit

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製品名:
Antiproliferative agent-77
製品番号:
HY-186161
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