Centrosomal protein of 170 kDa

Definition:

Plays a role in microtubule organization. Required for centriole subdistal appendage assembly.

References:

[1]. Ning Huang, et al. Hierarchical assembly of centriole subdistal appendages via centrosome binding proteins CCDC120 and CCDC68. Nat Commun. 2017 Apr 19;8:15057. [Content Brief]

[2]. Giulia Guarguaglini, et al. The forkhead-associated domain protein Cep170 interacts with Polo-like kinase 1 and serves as a marker for mature centrioles. Mol Biol Cell. 2005 Mar;16(3):1095-107. [Content Brief]

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