CAY10590
Based on 1 Customer Validation
CAY10590 (GK115) is an inhibitor of secreted phospholipase A2 (sPLA2) and can be used for the research of chronic inflammatory kidney diseases.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 1101136-50-8
- Formula: C21H33NO3
- Molecular Weight:347.49
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Phospholipase Isoforms
More
Biological Activity
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sPLA2 |
CAY10590 (GK115) (0-10 μM; 24 h) inhibits IL-1β/forskolin-stimulated PGE2 formation in mesangial cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1101136-50-8
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Appearance Solid
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Molecular Weight 347.49
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Formula C21H33NO3
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Color White to off-white
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SMILES
CCCC[C@@H](NC(CCCCCCC1=CC=CC=C1)=O)CCC(O)=O
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Synonyms
GK115
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 20 mg/mL (57.56 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8778 mL | 14.3889 mL | 28.7778 mL | 71.9445 mL |
| 5 mM | 0.5756 mL | 2.8778 mL | 5.7556 mL | 14.3889 mL | |
| 10 mM | 0.2878 mL | 1.4389 mL | 2.8778 mL | 7.1945 mL | |
| 15 mM | 0.1919 mL | 0.9593 mL | 1.9185 mL | 4.7963 mL | |
| 20 mM | 0.1439 mL | 0.7194 mL | 1.4389 mL | 3.5972 mL | |
| 25 mM | 0.1151 mL | 0.5756 mL | 1.1511 mL | 2.8778 mL | |
| 30 mM | 0.0959 mL | 0.4796 mL | 0.9593 mL | 2.3982 mL | |
| 40 mM | 0.0719 mL | 0.3597 mL | 0.7194 mL | 1.7986 mL | |
| 50 mM | 0.0576 mL | 0.2878 mL | 0.5756 mL | 1.4389 mL |
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