Des B30 Insulin 

Des B30 Insulin is a bioactive insulin analogue lacking the B30 amino acid residue. Des B30 Insulin can be used for the study of diabetes^[1].

5707.47

C₂₅₃H₃₇₇N₆₄O₇₅S₆

Chain1:Phe-Val-Asn-Gln-His-Leu-Cys-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cys-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Lys Chain2:Gly-Ile-Val-Glu-Gln-Cys-Cys-Thr-Ser-Ile-Cys-Ser-Leu-Tyr-Gln-Leu-Glu-Asn-Tyr-Cys-Asn (Disulfidebridge:Chain 1 Cys7-Chain 2 Cys7, Chain 1 Cys19-Chain 2 Cys20, Chain 2 Cys6-Chain 2 Cys11)

Chain1:FVNQHLCGSHLVEALYLVCGERGFFYTPK Chain2:GIVEQCCTSICSLYQLENYCN (Disulfidebridge:Chain 1 Cys7-Chain 2 Cys7, Chain 1 Cys19-Chain 2 Cys20, Chain 2 Cys6-Chain 2 Cys11)

O=C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CO)C(N[C@@H](CC(C)C)C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H](CSSC[C@@H](C(NCC(N[C@@H](CCC(O)=O)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CC5=CC=C(C=C5)O)C(N[C@@H]([C@H](O)C)C(N6[C@@H](CCC6)C(N[C@@H](CCCCN)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC7=O)C(N[C@@H](CC(N)=O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC8=O)C(N[C@@H](CS/O=C(N[C@@H](CS)C(NCC(N[C@@H](CO)C(N[C@@H](CC9=CNC=N9)C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CC%10=CC=C(C=C%10)O)C(N[C@@H](CC(C)C)C(N[C@H]7C(C)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)/[C@H](CC(C)C)NC([C@H](CC%11=CNC=N%11)NC([C@H](CCC(N)=O)NC([C@H](CC(N)=O)NC([C@H](C(C)C)NC([C@H](CC%12=CC=CC=C%12)N)=O)=O)=O)=O)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CO)C(N[C@H]8[C@@H](C)CC)=O)=O)=O)=O)=O)=O)=O)=O)CN

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Tofteng AP, et al. Total synthesis of desB30 insulin analogues by biomimetic folding of single-chain precursors. Chembiochem. 2008 Dec 15;9(18):2989-96.  [Content Brief]