Measles Virus Infection

Measles virus, an RNA virus belonging to the Paramyxoviridae family, is primarily known for causing a highly contagious systemic infection characterized by fever, cough, coryza, conjunctivitis, and a maculopapular rash. It is most closely associated with hepatitis among paramyxoviruses, with 10–20% of infected children exhibiting subclinical hepatic involvement; severe liver, pulmonary, or neurological complications may occur in immunocompromised individuals. Diagnosis relies on detection of measles-specific IgM antibodies in serum, viral isolation, or identification of viral RNA via PCR from respiratory secretions, blood, or tissue. No specific antiviral therapy is approved, though ribavirin may demonstrate some efficacy. Prevention is effectively achieved through live attenuated measles vaccination or post-exposure administration of intravenous immunoglobulin (IVIG).

References:

[1]. Measles Virus. sciencedirect.

Measles Virus Infection (1):

Targets:	DNA/RNA Synthesis (1)

Cat. No.	Product Name	CAS No.	Purity	Chemical Structure

HY-180882

GHP-88310
GHP-88310 (EIDD-3608) is a potent, orally active orthoparamyxovirus polymerases inhibitor. GHP-88310 exhibits potent activity against HPIV3 and related respiroviruses, measles virus (MeV) and related morbilliviruses. GHP-88310 exhibits efficacy in both canine distemper virus (CDV) ferret models and HPIV3 cotton rat models. GHP-88310 can be used for orthoparamyxovirus disease research.

Name
Email *

	Sorry, but the email address you supplied was invalid.