2. Anti-infection
  3. HPV
  4. E6AP-mimicking peptide

E6AP-mimicking peptide (compound 13) is a high-affinity, selective, irreversible and potent peptide-based covalent HPV16 E6 inhibitor targeting the 16E6 oncoprotein using a cysteine-reactive acrylamide warhead. E6AP-mimicking peptide has a Ki of 17 nM. E6AP-mimicking peptide targets all residues appearing in the binding pocket of E6 to disrupt the binding interface of 16E6 and E6AP. E6AP-mimicking peptide selectively binds and crosslinks to MBP-16E6 in PBS or a protein mixture.

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E6AP-mimicking peptide

E6AP-mimicking peptide 화학구조

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E6AP-mimicking peptide Related Antibodies

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제품 설명

E6AP-mimicking peptide (compound 13) is a high-affinity, selective, irreversible and potent peptide-based covalent HPV16 E6 inhibitor targeting the 16E6 oncoprotein using a cysteine-reactive acrylamide warhead. E6AP-mimicking peptide has a Ki of 17 nM. E6AP-mimicking peptide targets all residues appearing in the binding pocket of E6 to disrupt the binding interface of 16E6 and E6AP. E6AP-mimicking peptide selectively binds and crosslinks to MBP-16E6 in PBS or a protein mixture[1].

분자량

2630.09

화학식

C128H193N31O29
Sequence

{9-fluorenyl acetamido}-Ile-Pro-Gln-Ser-Ala-Glu-Leu-Thr-Leu-Gln-Glu-Leu-{Dha}-Arg-Arg-Lys-Lys-Lys(1-anthracenyl acetamido)-NH2
Sequence Shortening

{9-fluorenyl acetamido}-IPQSAELTLQELL-{Dha}-RRKK-{Lys(1-anthracenyl acetamido)}-NH2
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
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E6AP-mimicking peptide Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

E6AP-mimicking peptideHPVHuman papillomavirusIrreversiblecovalentHPV16 E6cysteine-reactive acrylamide warhead16E6E6APMBP-16E6Inhibitorinhibitorinhibit

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상품명:
E6AP-mimicking peptide
Cat. No.:
HY-P10428
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