Fluocortin butyl ester 

Fluocortin butyl ester is a developed corticosteroid compound with no detectable systemic corticosteroid activity when it is used topically. Fluocortin butyl ester appears to be an effective well-tolerated topical steroid useful in the research of perennial rhinitis^[1].

Fluocortin butyl ester dose not depress the resistance of the animals against microbial infections even after repeated s.c. or oral administration of dosages up to 100 mg/kg^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

446.55

C₂₆H₃₅FO₅

41767-29-7

C[C@]([C@H]1C(C(OCCCC)=O)=O)(C2)[C@](C[C@H]1C)([H])[C@@](C[C@@H]3F)([H])[C@@]([C@H]2O)([H])[C@](C3=CC4=O)(C=C4)C

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Hartley TF, et al. Efficacy and tolerance of fluocortin butyl administered twice daily in adult patients with perennial rhinitis. J Allergy Clin Immunol. 1985;75(4):501-507.  [Content Brief]

  [2]. [2] Kessler HJ et al. Tierexperimentelle Untersuchungen über den Einfluss von Fluocortin-butylester auf den Verlauf generalisierter Infektionen [Experimental studies in animals on the influence of fluocortin butylester on the course of generalized infections (author's transl)]. Arzneimittelforschung. 1977;27(11a):2214-2216.  [Content Brief]