2. Metabolic Enzyme/Protease
  3. Factor XI
  4. FXIa-IN-16

FXIa-IN-16 (Compound 43) is an orally active and selective Factor XIa (FXIa) inhibitor with an IC50 of 0.19 nM. FXIa-IN-16 exhibits strong anticoagulant and antithrombotic activities and shows good safety in mice. FXIa-IN-16 can be used in the research related to the treatment of thrombosis.

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FXIa-IN-16

FXIa-IN-16 Estructura química

No. CAS : 3046390-69-3

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FXIa-IN-16 Related Antibodies

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Descripciòn

FXIa-IN-16 (Compound 43) is an orally active and selective Factor XIa (FXIa) inhibitor with an IC50 of 0.19 nM. FXIa-IN-16 exhibits strong anticoagulant and antithrombotic activities and shows good safety in mice. FXIa-IN-16 can be used in the research related to the treatment of thrombosis[1].

Peso molecular

504.90

Fòrmula

C24H18ClFN8O2
No. CAS
SMILES

O=C1N(CC2=NC=CC(C3=C(F)N=C(N)C=C3)=C2)C=C(OC)C(C4=CC(Cl)=CC=C4N5C=NN=N5)=C1
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Room temperature in continental US; may vary elsewhere.
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Pureza y Documentación
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FXIa-IN-16 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FXIa-IN-163046390-69-3Factor XIAC16HK-2HepG2Arterial thrombosis modelInhibitorinhibitorinhibit

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Nombre del producto:
FXIa-IN-16
Cat. No.:
HY-172400
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