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  3. Drug Intermediate
  4. Garbanzol

Garbanzol is an orally active natural flavonoid compound. Garbanzol is one of the key intermediates in the flavonoid biosynthetic pathway. Garbanzol exhibits anti-mutagenic activity.

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Garbanzol

Garbanzol Estructura química

No. CAS : 1226-22-8

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Garbanzol Related Antibodies

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Descripciòn

Garbanzol is an orally active natural flavonoid compound. Garbanzol is one of the key intermediates in the flavonoid biosynthetic pathway. Garbanzol exhibits anti-mutagenic activity[1][2].

Cellular Effect
Cell Line Type Value Description References
A549 IC50
> 100 3
Compound: 8
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
[PMID: 18440233]
A549 IC50
> 100 3
Compound: 8
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
[PMID: 18440233]
A549 IC50
>100 3
Compound: 8
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
[PMID: 18440233]
B16-BL6 IC50
> 100 3
Compound: 8
Cytotoxicity against mouse B16-BL6 cells after 72 hrs by MTT assay
Cytotoxicity against mouse B16-BL6 cells after 72 hrs by MTT assay
[PMID: 18440233]
B16-BL6 IC50
>100 3
Compound: 8
Cytotoxicity against mouse B16-BL6 cells after 72 hrs by MTT assay
Cytotoxicity against mouse B16-BL6 cells after 72 hrs by MTT assay
[PMID: 18440233]
B16-BL6 IC50
> 100 3
Compound: 8
Cytotoxicity against mouse B16-BL6 cells after 72 hrs by MTT assay
Cytotoxicity against mouse B16-BL6 cells after 72 hrs by MTT assay
[PMID: 18440233]
HeLa IC50
>100 3
Compound: 8
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
[PMID: 18440233]
HeLa IC50
> 100 3
Compound: 8
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
[PMID: 18440233]
HT-1080 IC50
> 100 3
Compound: 8
Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay
Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay
[PMID: 18440233]
HT-1080 IC50
>100 3
Compound: 8
Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay
Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay
[PMID: 18440233]
HeLa IC50
> 100 3
Compound: 8
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
[PMID: 18440233]
HT-1080 IC50
> 100 3
Compound: 8
Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay
Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay
[PMID: 18440233]
Lewis lung carcinoma cell line IC50
> 100 3
Compound: 8
Cytotoxicity against mouse LLC cells after 72 hrs by MTT assay
Cytotoxicity against mouse LLC cells after 72 hrs by MTT assay
[PMID: 18440233]
Lewis lung carcinoma cell line IC50
>100 3
Compound: 8
Cytotoxicity against mouse LLC cells after 72 hrs by MTT assay
Cytotoxicity against mouse LLC cells after 72 hrs by MTT assay
[PMID: 18440233]
In Vitro

Garbanzol (0.125-0.250 mg/plate; 48 h) exhibits no antimutagenic activity against aflatoxin B1-induced mutagenicity in Salmonella typhimurium TA100, but shows significant antimutagenic activity against MNNG-induced mutagenicity at 0.125 mg/plate and weak activity at 0.250 mg/plate[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Garbanzol Related Antibodies
Parmacokinetics
Species Dose Route Cmax AUC Tmax T1/2 MRT0-t
Rat[2] 1.154 mg/kg p.o. 0.24 0.41 0.60 h 5.44 h 2.52 h
Peso molecular

272.25

Fòrmula

C15H12O5
No. CAS
Appearance

Solid

Color

White to off-white

SMILES

O[C@@H]1[C@@H](C2=CC=C(O)C=C2)OC3=CC(O)=CC=C3C1=O
Structure Classification
Initial Source
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Pureza y Documentación
Referencias
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Garbanzol Related Classifications

  • Calculadora de molaridad

  • Calculadora de dilución

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Garbanzol1226-22-8Drug IntermediateDrug Iintermediateflavonoid compoundintermediates
Inhibitorinhibitorinhibit

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Nombre del producto:
Garbanzol
Cat. No.:
HY-N3926
Cantidad:
MCE Japan Authorized Agent:

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