1. Gene
  2. NPY2R - neuropeptide Y receptor Y2 Gene

NPY2R - neuropeptide Y receptor Y2 Gene

Homo sapiens

Also known as NPY2-R

Gene ID: 4887 | Gene type: protein coding

About NPY2R

Cytogenetic location: 4q32.1 Genomic coordinates (GRCh38): 4:155,173,723-155,217,076 (from NCBI)

This gene has 2 transcripts (splice variants), 248 orthologues and 33 paralogues. Low expression observed in reference dataset.

Summary

Predicted to enable Calcium Channel regulator activity and Neuropeptide Y Receptor activity. Involved in cardiac left ventricle morphogenesis and outflow tract morphogenesis. Located in cilium. Implicated in Huntington's disease; morbid obesity; and obesity. Biomarker of peripheral artery disease and temporal lobe epilepsy. [provided by Alliance of Genome Resources, Apr 2022]

NPY2R Products(3)

mRNA Protein Name
NM_001375470.1 NP_001362399.1 neuropeptide Y receptor type 2
NM_001370180.1 NP_001357109.1 neuropeptide Y receptor type 2
NM_000910.4 NP_000901.1 neuropeptide Y receptor type 2

NPY2R Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (67 - 325)

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  • 381 a.a.
Protein Preferred Names Protein Names

neuropeptide Y receptor type 2

NPY-Y2 receptor

Related Diseases

Diseases Alias
Nephronophthisis 4

NPHP4

Juvenile Nephronophthisis 4

Nephronophthisis 4, Juvenile

Nephronophthisis, Type 4

Epilepsy

Epilepsy Syndrome

Epileptic Syndrome

Epilepsies

Symptomatic Epilepsies

Post Traumatic Epilepsy

Traumatic Epilepsy

Traumatic Epileptic

Epilepsy Due To Hippocampal Sclerosis

Epilepsy With Ammon'S Horn Sclerosis

Epilepsy Due To Cortical Dysplasia

Epilepsy Due To Neuronal Migration Disorders

Peripheral Artery Disease

Peripheral Arterial Disease

Peripheral Arterial Diseases

Temporal Lobe Epilepsy

Epilepsy, Temporal Lobe

Epilepsy Temporal Lobe

Joubert Syndrome 1

Joubert Syndrome

Jbts

Cerebellooculorenal Syndrome 1

JBTS1

Joubert-Boltshauser Syndrome

Cerebelloparenchymal Disorder Iv

Cpd4

Cors1

Joubert Syndrome And Related Disorders

Jsrd

Familial Aplasia Of The Vermis

Joubert Syndrome Related Disorders

Js

Cerebellar Vermis Agenesis

Cerebelloparenchymal Disorder 4

Agenesis Of Cerebellar Vermis

Cerebello-Oculo-Renal Syndrome

Cors

Joubert-Bolthauser Syndrome

Cpd Iv

Classic Joubert Syndrome

Joubert Syndrome Type A

Pure Joubert Syndrome

Cerebello-Oculo-Renal Syndrome 1

Joubert Syndrome-1

Joubert Syndrome, Type 1

Joubert'S Syndrome

Huntington Disease

Huntington'S Disease

Huntington Chorea

HD

Huntington'S Chorea

Huntington Chronic Progressive Hereditary Chorea

Juvenile Huntington Disease

Chronic Progressive Chorea

Chronic Progressive Hereditary Chorea

Hc - [Huntington Chorea]

Hereditary Chorea

Progressive Hereditary Chorea

Body Mass Index Quantitative Trait Locus 11

OBESITY

Obesity, Susceptibility To

Leanness, Inherited

Obesity, Susceptibility To, Bmiq11

Obesity, Mild, Early-Onset

Obesity, Association With

Obesity, Early-Onset, Susceptibility To

Obesity, Severe

Obesity, Severe, And Type Ii Diabetes

Obesity, Late-Onset

BMIQ11

Obesity Bmiq11

Obesity, Early-Onset

Obesity , Susceptibility To

Simple Obesity Nos

Excess Fat

Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified

Adiposis

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Mus musculus NPY2R MGD MGI:108418
Rattus norvegicus NPY2R RGD RGD:620475
Felis catus NPY2R VGNC VGNC:78538
Macaca mulatta NPY2R VGNC VGNC:100257
Bos taurus NPY2R VGNC VGNC:52806
Others NPY2R NCBI