BAIAP3 - BAI1 associated protein 3 Gene

Homo sapiens

Also known as BAP3

Gene ID: 8938 | Gene type: protein coding

About BAIAP3

Cytogenetic location: 16p13.3 Genomic coordinates (GRCh38): 16:1,333,645-1,349,439 (from NCBI)

This gene has 16 transcripts (splice variants), 159 orthologues and 1 paralogue. Broad expression in adrenal (RPKM 9.7), brain (RPKM 8.5) and 19 other tissues.

Summary

This p53-target gene encodes a brain-specific angiogenesis inhibitor. The protein is a seven-span transmembrane protein and a member of the Secretin Receptor family. It interacts with the cytoplasmic region of brain-specific angiogenesis inhibitor 1. This protein also contains two C2 domains, which are often found in proteins involved in signal transduction or membrane trafficking. Its expression pattern and similarity to other proteins suggest that it may be involved in synaptic functions. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]

BAIAP3 Products(6)

mRNA	Protein	Name
NM_001199096.2	NP_001186025.1	BAI1-associated protein 3 isoform 2
NM_001199097.2	NP_001186026.1	BAI1-associated protein 3 isoform 3
NM_001199098.2	NP_001186027.1	BAI1-associated protein 3 isoform 4
NM_001199099.2	NP_001186028.1	BAI1-associated protein 3 isoform 5
NM_001286464.2	NP_001273393.2	BAI1-associated protein 3 isoform 6
NM_003933.5	NP_003924.2	BAI1-associated protein 3 isoform 1

BAIAP3 Protein Structure

Membr_traf_MHD

0
200
400
600
800
1000
1187 a.a.

Protein Preferred Names

Protein Names

BAI1-associated protein 3

BAI-associated protein 3

Related Diseases

Diseases

Alias

Alpha Thalassemia-Intellectual Disability Syndrome Type 1

Alpha Thalassemia-Intellectual Disability Syndrome, Deletion Type	Alpha-Thalassemia-Intellectual Disability Syndrome Linked To Chromosome 16
Atr Syndrome Linked To Chromosome 16	Atr Syndrome, Deletion Type
Atr-16 Syndrome	Alpha Thalassemia-Retardation Syndrome
Alpha-Thalassemia/Mental Retardation Syndrome, Deletion-Type	Alpha-Thalassemia/Mental Retardation Syndrome, Type 1
Alpha-Thalassemia Mental Retardation Syndrome, Deletion-Type

Desmoplastic Small Round Cell Tumor

Dsrct	Desmoplastic Small Round-Cell Tumor
Desmoplastic Small Round-Cell Neoplasm

Short-Rib Thoracic Dysplasia 9 With Or Without Polydactyly

Conorenal Syndrome	Saldino-Mainzer Syndrome
SRTD9	Mainzer-Saldino Syndrome
Mzsds	Mainzer-Saldino Disease
Renal Dysplasia, Retinal Pigmentary Dystrophy, Cerebellar Ataxia, And Skeletal Dysplasia	Renal Dysplasia, Retinal Pigmentary Dystrophy, Cerebellar Ataxia And Skeletal Dysplasia
Renal Dysplasia, Retinal Pigmentary Dystrophy, Cerebellar Ataxia And Skeletal Dy	Mainzer Saldino Syndrome
Conorenal Dysplasia	Mainzer-Saldino Chondrodysplasia
Saldino-Mainzer Dysplasia	Short-Rib Thoracic Dysplasia 9
Renal Dysplasia-Retinal Pigmentary Dystrophy-Cerebellar Ataxia-Skeletal Dysplasia Syndrome	Mss
Renal Dysplasia Retinal Pigmentary Dystrophy Cerebellar Ataxia And Skeletal Dysplasia

Heinz Body Anemias

Heinz Body Anemia	Heinz Body Anemias, Alpha-
HEIBAN	Anemia, Heinz Body
Acquired Heinz Body Anemia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01356	BAIAP3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	BAIAP3	MGD	MGI:2685783
Canis familiaris	BAIAP3	VGNC	VGNC:38374
Macaca mulatta	BAIAP3	VGNC	VGNC:70223
Rattus norvegicus	BAIAP3	RGD	RGD:10059729
Bos taurus	BAIAP3	VGNC	VGNC:26415

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