MPZL1 - myelin protein zero like 1 Gene
Also Known as PZR; PZRa; PZRb; PZR1b; MPZL1b
Species: Homo sapiens
About MPZL1
Ubiquitous expression in gall bladder (RPKM 26.1), placenta (RPKM 23.6) and 25 other tissues.
Summary
Predicted to enable structural molecule activity. Predicted to be involved in cell-cell signaling and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to act upstream of or within positive regulation of cell migration. Located in cell surface and focal adhesion. [provided by Alliance of Genome Resources, Apr 2022]
MPZL1 Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_001146191.2 | NP_001139663.1 | myelin protein zero-like protein 1 isoform c precursor |
| NM_003953.6 | NP_003944.1 | myelin protein zero-like protein 1 isoform a precursor |
| NM_024569.5 | NP_078845.3 | myelin protein zero-like protein 1 isoform b precursor |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
9792637 | GOA |
MPZL1 Protein Structure
V-set: Immunoglobulin V-set domain (39 - 154)
- 0
- 100
- 200
- 269 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
myelin protein zero-like protein 1 |
|
MPZL1 Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
MPZL1 | O95297 | MFF | Homo sapiens | Q9GZY8-5 | 32296183 | |
|
Intra
|
MPZL1 | O95297 | MFF | Homo sapiens | Q9GZY8-5 | 32296183 | |
|
Intra
|
MPZL1 | O95297 | MFF | Homo sapiens | Q9GZY8-5 | 32296183 | |
|
Intra
|
MPZL1 | O95297 | PTPN11 | Homo sapiens | Q06124 | 33961781 |
Recombinant MPZL1 Proteins
| Cat. No. | Product Name | Accession | Purity |
|---|---|---|---|
| HY-P70220 | MPZL1 Protein, Human (HEK293, His) | O95297 (S36-V162) | ≥ 95%, as determined by reducing SDS-PAGE. |
MPZL1 Antibodies
| Cat. No. | Product Name | Application | Reactivity |
|---|---|---|---|
| HY-P83533 | Myelin Protein Zero Antibody (YA3278) | WB | Rat |
| HY-P83533A | Myelin Protein Zero Antibody (YA3278)(PBS only) | WB | Rat |
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Noonan Syndrome With Multiple Lentigines |
|
|
| Charcot-Marie-Tooth Disease |
|
|
| Rasopathy |
|
|
| Noonan Syndrome 1 |
|
|
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Mus musculus | MPZL1 | MGD | MGI:1915731 |
| Felis catus | MPZL1 | VGNC | VGNC:68313 |
| Rattus norvegicus | MPZL1 | RGD | RGD:1359140 |
| Macaca mulatta | MPZL1 | VGNC | VGNC:100012 |
| Bos taurus | MPZL1 | VGNC | VGNC:31592 |
| Canis familiaris | MPZL1 | VGNC | VGNC:43354 |
| Others | MPZL1 | NCBI |