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  3. KB-05

KB-05 is an electrophilic fragment molecule that can be used in DIA-based quantitative chemical proteomic screening studies.

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KB-05

KB-05 Chemische Struktur

CAS. Nr. : 1956368-15-2

Größe Preis Verfügbarkeit Menge
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
Auf Lager
Solution
10 mM * 1 mL in DMSO Auf Lager
Solid
5 mg Auf Lager
10 mg Auf Lager
25 mg Auf Lager
50 mg Auf Lager
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200 mg   Angebot einholen  

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Beschreibung

KB-05 is an electrophilic fragment molecule that can be used in DIA-based quantitative chemical proteomic screening studies.

In Vitro

KB-05 is an electrophilic small molecule fragment whose active group is commonly found in covalent chemical probes and drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molekulargewicht

302.17

Formel

C15H12BrNO

CAS. Nr.
Appearance

Solid

Color

White to yellow

SMILES

O=C(N(C1=CC=C(C=C1)Br)C2=CC=CC=C2)C=C

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Lösungsmittel & Löslichkeit
In Vitro: 

DMSO : 100 mg/mL (330.94 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3094 mL 16.5470 mL 33.0940 mL
5 mM 0.6619 mL 3.3094 mL 6.6188 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molaritätsrechner

  • Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Reinheit & Dokumentation

Purity: 99.83%

Verweise

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.3094 mL 16.5470 mL 33.0940 mL 82.7349 mL
5 mM 0.6619 mL 3.3094 mL 6.6188 mL 16.5470 mL
10 mM 0.3309 mL 1.6547 mL 3.3094 mL 8.2735 mL
15 mM 0.2206 mL 1.1031 mL 2.2063 mL 5.5157 mL
20 mM 0.1655 mL 0.8273 mL 1.6547 mL 4.1367 mL
25 mM 0.1324 mL 0.6619 mL 1.3238 mL 3.3094 mL
30 mM 0.1103 mL 0.5516 mL 1.1031 mL 2.7578 mL
40 mM 0.0827 mL 0.4137 mL 0.8273 mL 2.0684 mL
50 mM 0.0662 mL 0.3309 mL 0.6619 mL 1.6547 mL
60 mM 0.0552 mL 0.2758 mL 0.5516 mL 1.3789 mL
80 mM 0.0414 mL 0.2068 mL 0.4137 mL 1.0342 mL
100 mM 0.0331 mL 0.1655 mL 0.3309 mL 0.8273 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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KB-05
Art. -Nr.:
HY-149461
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