1. Metabolic Enzyme/Protease
  2. MAGL
  3. MAGL-IN-9

MAGL-IN-9 (compound 16) is a selective and reversible MAGL inhibitor with IC50 2.7 nM.

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MAGL-IN-9

MAGL-IN-9 화학구조

CAS No. : 3017151-74-2

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제품 설명

MAGL-IN-9 (compound 16) is a selective and reversible MAGL inhibitor with IC50 2.7 nM[1].

IC50 & Target

IC50: 2.7 nM (MAGL)[1]

In Vitro

MAGL-IN-9 (10 μM, 25 min) selectively inhibits MAGL in mouse brain membrane preparations, without affecting other serine hydrolases such as FAAH, ABHD6, and ABHD12[1].
MAGL-IN-9 shows a reversible inhibition mechanism in both preincubation and dilution tests[1].
MAGL-IN-9 inhibits MAGL in U973 cells with an IC50 value of 193 nM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

490.51

화학식

C25H22F4N2O2S

CAS No.
SMILES

O=C(N1CCC(CC2=CC=C(F)C(SC3=NC=CC(C(F)(F)F)=C3)=C2)CC1)C4=CC=CC(O)=C4

선적

Room temperature in continental US; may vary elsewhere.

보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

상품명:
MAGL-IN-9
Cat. No.:
HY-157040
수량:
MCE Japan Authorized Agent: