2. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-Labeled Compounds

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Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.

MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds (12430):

Cat. No. 상품명 CAS No. Purity 화학구조
  • HY-B0575S
    Triamterene-d5 1189922-23-3 99.82%
    Triamterene-d5 is deuterium labeled Triamterene (HY-B0575). Triamterene blocks epithelial Na+ channel (ENaC) in a voltage-dependent manner, which used as a mild diuretic. Triamterene is an inhibitor of the TGR5 receptor.
    Triamterene-d5
  • HY-B0631S
    Alendronic acid-d6 1035437-39-8 98.0%
    Alendronic acid-d6 is the deuterium labeled Alendronic acid. Alendronic acid, a bisphosphonate, is a farnesyl diphosphate synthase (FDPS) inhibitor. Alendronic acid inhibits osteoclast-mediated bone resorption. Alendronic acid shows efficacy in postmenopausal osteoporosis, malignant hypercalcemia and Paget’s disease.
    Alendronic acid-d6
  • HY-B0659S
    Brimonidine-d4 1184971-51-4 99.13%
    Brimonidine-d4 is the deuterium labeled Brimonidine. Brimonidine (UK 14304) is a full α2-adrenergic receptor (α2-AR) agonist.
    Brimonidine-d4
  • HY-B1046S
    Clofazimine-d7 99.0%
    Clofazimine-d7 is deuterium labeled Clofazimine. Clofazimine is an iminophenazine dye, has a marked anti-inflammatory effect, has been used in combination with other antimycobacterial agents to treat AIDS and Crohn's disease.
    Clofazimine-d7
  • HY-B1188S
    Propantheline-d3 bromide 64717-35-7 99.00%
    Propantheline-d3 (bromide) is the deuterium labeled Propantheline bromide. Propantheline bromide is an antimuscarinic agent, used for the treatment of hyperhidrosis, cramps or spasms of the stomach, intestines or bladder, and enuresis.
    Propantheline-d3 bromide
  • HY-B1244S
    Dimetridazole-d3 64678-69-9 99.78%
    Dimetridazole-d3 (1,2-Dimethyl-5-nitroimidazole-d3) is a deuterium labeled Dimetridazole (HY-B1244). Dimetridazole is a nitroimidazole antibiotic. Dimetridazole inhibits protein synthesis in cultures of Campylobacter jejuni. Dimetridazole is genotoxic. Dimetridazole can be used in the research of protozoal and bacterial infections.
    Dimetridazole-d3
  • HY-B1270S
    Isoxsuprine-d6 hydrochloride 2706004-35-3 99.9%
    Isoxsuprine-d6 (hydrochloride) is the deuterium labeled Isoxsuprine hydrochloride. Isoxsuprine hydrochloride is a beta-adrenergic receptor agonist with Kis of 13.65 μΜ and 3.48 μΜ for myometrial and placcntal beta-adrenergic receptor, respectively. Isoxsuprine hydrochloride is also a NMDA receptor antagonist.
    Isoxsuprine-d6 hydrochloride
  • HY-B1805S
    Triclocarban-d4 1219799-29-7 98.09%
    Triclocarban-d4 is the deuterium labeled Triclocarban. Triclocarban (3,4,4′-Trichlorocarbanilide), a broad spectrum antibacterial compound, is widely used in a broad range of applications such as the production of soaps, skin creams, toothpastes and deodorants. Triclocarban is a potential endocrine-disrupting chemical with the capacity to modulate androgen and estrogen activities as well as other hormone-mediated biological processes.
    Triclocarban-d4
  • HY-B1944S
    Dipropyl phthalate-d4 358731-29-0 99.02%
    Dipropyl phthalate-d4 is the deuterium labeled Dipropyl phthalate.
    Dipropyl phthalate-d4
  • HY-B2130S
    Uric acid-13C,15N3 2421217-23-2 ≥99.0%
    Uric acid-13C,15N3 is the 13C-labeled and 15N-labeled Uric acid. Uric acid, scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation.
    Uric acid-13C,15N3
  • HY-B2157S
    Robenidine-d8 hydrochloride 1173097-77-2 99.0%
    Robenidine-d8 (hydrochloride) is the deuterium labeled Robenidine hydrochloride. Robenidine hydrochloride is an anticoccidial agent which is also active against MRSA and VRE with MIC50s of 8.1 and 4.7 μM, respectively.
    Robenidine-d8 hydrochloride
  • HY-I0508S
    Phthalic acid-d4 87976-26-9 98.36%
    Phthalic acid-d4 is the deuterium labeled Phthalic acid. Phthalic acid is the final common metabolite of phthalic acid esters (PAEs). Phthalic acid can be used for the synthesis of synthetic agents, such as isophthalic acid (IPA), and terephthalic acid (TPA). Phthalic acid has applications in the preparation of phthalate ester plasticizers. Phthalic acid exhibits mutagenic effect and causes genetic damage in mammalian germ cells.
    Phthalic acid-d4
  • HY-I0983S
    1,1,3,3-Tetramethylurea-d12 51219-89-7 98.17%
    1,1,3,3-Tetramethylurea-d12 is the deuterium labeled 1,1,3,3-Tetramethylurea.
    1,1,3,3-Tetramethylurea-d12
  • HY-N0111S
    Coenzyme Q10-d6 110971-02-3 98.35%
    Coenzyme Q10-d6 is deuterium labeled Coenzyme Q10. Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.
    Coenzyme Q10-d6
  • HY-N0180S
    18β-Glycyrrhetinic acid-d3 98.92%
    18β-Glycyrrhetinic acid-d3 is deuterium labeled 18β-Glycyrrhetinic acid. 18β-Glycyrrhetinic acid is the major bioactive component of Glycyrrhizae Radix and possesses anti-ulcerative, anti-inflammatory and antiproliferative properties.
    18β-Glycyrrhetinic acid-d3
  • HY-N0230S
    β-Alanine-13C3,15N 285978-07-6 99.99%
    β-Alanine-13C3,15N is the 13C- and 15N-labeled β-Alanine. β-Alanine is a non-essential amino acid that is shown to be metabolized into carnosine, which functions as an intracellular buffer.
    β-Alanine-13C3,15N
  • HY-N0453S
    Hypericin-d10
    Hypericin-d10 is the deuterium labeled Hypericin. Hypericin is a photosensitive antiviral with anticancer and antidepressant agent derived from Hypericum perforatum. It can inhibit tyrosine kinases with IC50 of 7.5 μM.
    Hypericin-d10
  • HY-N0471S
    L-Hyoscyamine-d3 3032205-96-9 ≥98.0%
    L-Hyoscyamine-d3 is the deuterium labeled L-Hyoscyamine. L-Hyoscyamine (Daturine), a natural plant tropane alkaloid, is a potent and competitive muscarinic receptor (MR) antagonist. L-Hyoscyamine is a levo-isomer to Atropine (HY-B1205).
    L-Hyoscyamine-d3
  • HY-N0898S
    Catechin-13C3 1261254-33-4 98.06%
    Catechin-13C3 is the 13C-labeled Catechin. Catechin ((+)-Catechin) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.
    Catechin-13C3
  • HY-N1201S
    Apigenin-d5 263711-74-6 98.90%
    Apigenin-d5 is a deuterated labeled Apigenin. Apigenin (4',5,7-Trihydroxyflavone) is a competitive CYP2C9 inhibitor with a Ki of 2 μM.
    Apigenin-d5