2. Academic Validation
  3. Two new triterpenoid saponins from Platycodon grandiflorum

Two new triterpenoid saponins from Platycodon grandiflorum

  • Chem Pharm Bull (Tokyo). 1999 Jun;47(6):903-4. doi: 10.1248/cpb.47.903.
T Nikaido 1,  K Koike,  K Mitsunaga,  T Saeki
Affiliations

Affiliation

  • 1 School of Pharmaceutical Sciences, Toho University, Chiba, Japan.
PMID: 10399842 DOI: 10.1248/cpb.47.903
Abstract

Two new triterpenoid saponins, platycoside D [3-O-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyl-(1-->6)-beta-D- glucopyranosyl-2 beta, 3 beta, 16 alpha, 23-tetrahydroxyolean-12-ene-28-oic acid 28-O-beta-D- apiofuranosyl-(1-->3)-beta-D-xylopyranosyl-(1-->4)-alpha-L-rhamnop yranosyl- (1-->2)-alpha-L-arabinopyranoside] and platycoside E [3-O-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyl- (1-->6)-beta-D-glucopyranosyl-2 beta,3 beta,16 alpha,23,24-pentahydroxyolean-12-ene-28-oic acid 28-O-beta-D-apiofuranosyl-(1-->3)-beta-D-xylopyranosyl-(1-->4)-alp ha-L- rhamnopyranosyl-(1-->2)-alpha-L-arabinopyranoside] were isolated from the roots of Platycodon grandiflorum. Structural determination is based on spectral and chemical evidence.

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