2. Academic Validation
  3. Robinlin: a novel bioactive homo-monoterpene from Robinia pseudoacacia L. (Fabaceae)

Robinlin: a novel bioactive homo-monoterpene from Robinia pseudoacacia L. (Fabaceae)

  • Bioorg Med Chem Lett. 2001 Oct 8;11(19):2603-6. doi: 10.1016/s0960-894x(01)00514-5.
F Tian 1,  C J Chang,  J B Grutzner,  D E Nichols,  J L McLaughlin
Affiliations

Affiliation

  • 1 Department of Medicinal Chemistry and Molecular Pharmacology, School of Pharmacy and Pharmacal Sciences, School of Science, Purdue University, West Lafayette, IN 47907, USA.
PMID: 11551759 DOI: 10.1016/s0960-894x(01)00514-5
Abstract

A bioactivity-directed fractionation of the ethanolic extracts of Robinia pseudoacacia L. (Fabaceae) afforded robinlin (1), a novel homo-monoterpene. The structure of 1 was elucidated by spectral analyses of the parent compound as well as its derivatives; 1 showed strong bioactivity in the brine shrimp lethality test (BST).

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