2. Academic Validation
  3. Coumaroyl flavonol glycosides from the leaves of Ginkgo biloba

Coumaroyl flavonol glycosides from the leaves of Ginkgo biloba

  • Phytochemistry. 2001 Dec;58(8):1251-6. doi: 10.1016/s0031-9422(01)00320-x.
Y Tang 1,  F Lou,  J Wang,  Y Li,  S Zhuang
Affiliations

Affiliation

  • 1 Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210038, PR China. [email protected]
PMID: 11738417 DOI: 10.1016/s0031-9422(01)00320-x
Abstract

Two coumaroyl flavonol glycosides, isorhamnetin 3-O-alpha-L-[6"'-p-coumaroyl-(beta-D)-glucopyranosyl-(1,2)-rhamnopyranoside], and kaempferol 3-O-alpha-L-[6"'-p-coumaroyl-(beta-D)-glucopyranosyl-(1,2)-rhamnopyranoside]-7-O-beta-D-glucopyranoside, were isolated from the n-BuOH extract of Ginkgo biloba leaves. These two, together with six other flavonol glycosides, kaempferol 3-O-alpha-L-[6"'-p-coumaroyl-(beta-D)-glucopyranosyl-(1,2)-rhamnopyranoside], quercetin 3-O-alpha-L-[6"'-p-coumaroyl-(beta-D)-glucopyranosyl-(1,2)-rhamnopyranoside], quercetin 3-O-alpha-L-[6"'-p-coumaroyl-(beta-D)-glucopyranosyl-(1,2)-rhamnopyranoside]-7-O-beta-D-glucopyranoside, quercetin 3-O-beta-D-glucopyranosyl-(1-2)-alpha-L-rhamnopyranoside, quercetin 3-O-beta-rutinoside, and quercetin 3-O-beta-D-glucopyranoside, showed profound antioxidant activities in DPPH and cytochrome-c reduction assays using the HL-60 Cell Culture system.

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