2. Academic Validation
  3. Bisnortriterpenes from Salacia madagascariensis

Bisnortriterpenes from Salacia madagascariensis

  • J Nat Prod. 2005 Feb;68(2):251-4. doi: 10.1021/np0497088.
Deborah A Thiem 1,  Albert T Sneden,  Shabana I Khan,  Babu L Tekwani
Affiliations

Affiliation

  • 1 Department of Chemistry, Virginia Commonwealth University, P.O. Box 842006, Richmond, VA 23284-2006, USA.
PMID: 15730255 DOI: 10.1021/np0497088
Abstract

A new bisnortriterpene quinone methide, 20-epi-isoiguesterinol (2), and a new 6-oxophenolic triterpene, 6-oxoisoiguesterin (5), as well as two known compounds, isoiguesterin (1) and isoiguesterinol (4), were isolated from the petroleum ether extract of the roots of Salacia madagascariensis. Isoiguesterin (1) and 20-epi-isoiguesterinol (2) showed potent activity against Leishmania.

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