2. Academic Validation
  3. Bio-guided isolation of antioxidants from the stems of Dendrobium aurantiacum var. denneanum

Bio-guided isolation of antioxidants from the stems of Dendrobium aurantiacum var. denneanum

  • Phytother Res. 2007 Jul;21(7):696-8. doi: 10.1002/ptr.2133.
Li Yang 1,  Haofeng Han,  Norio Nakamura,  Masao Hattori,  Zhengtao Wang,  Luoshan Xu
Affiliations

Affiliation

  • 1 Key Laboratory of Standardization of Chinese Medicines of Ministry of Education, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, 201203 Shanghai, PR China.
PMID: 17421059 DOI: 10.1002/ptr.2133
Abstract

Bio-guided fractionation of the stems of Dendrobium aurantiacum var. denneanum using a 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical scavenging assay, led to the isolation of three 2-glucosyloxycinnamic acid derivates, namely, cis-melilotoside, trans-melilotoside and dihydromelilotoside, respectively. Their structures were elucidated through the analysis of uni- and bi-dimensional NMR, UV, IR and MS data. All these three compounds were first reported from the genus Dendrobium and exhibited potent antioxidant activities.

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