2. Academic Validation
  3. The metabolites of a mangrove endophytic fungus, Penicillium thomi

The metabolites of a mangrove endophytic fungus, Penicillium thomi

  • J Asian Nat Prod Res. 2007 Mar;9(2):159-64. doi: 10.1080/10286020500480423.
G Chen 1,  Y Zhu,  H-Z Wang,  S-J Wang,  R-Q Zhang
Affiliations

Affiliation

  • 1 Department of Biological Science and Biotechnology, Tsinghua University, Beijing, China.
PMID: 17454313 DOI: 10.1080/10286020500480423
Abstract

The chemical constituents research of the fermentation of Penicillium thomi separated from the root of Bruguiera gymnorrhiza led to the isolation of a new compound, 4',5-dihydroxy-2,3-dimethoxy-4-(hydroxypropyl)-biphenyl (1) and 11 known compounds. The structures of isolated compounds were determined by spectroscopic and chemical analysis. Their cytotoxic effects against three human Cancer cell lines (A549, HepG2 and HT29) were also investigated.

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