2. Academic Validation
  3. Pyronane monoterpenoids from the fruit of Gardenia jasminoides

Pyronane monoterpenoids from the fruit of Gardenia jasminoides

  • J Nat Prod. 2008 Jun;71(6):995-9. doi: 10.1021/np800002z.
Quan Cheng Chen 1,  UiJoung Youn,  Byung-Sun Min,  KiHwan Bae
Affiliations

Affiliation

  • 1 College of Pharmacy, Chungnam National University, Daejeon 305-764, Korea.
PMID: 18505286 DOI: 10.1021/np800002z
Abstract

Five new pyronane-type monocyclic monoterpenoids, jasminodiol (1), jasminoside H (6), 6'-O-sinapoyljasminoside A (7), 6'-O-sinapoyljasminoside C (8), and jasminoside I (9), together with four known analogues, were isolated from the fruit of Gardenia jasminoides. The structures of the new metabolites were characterized using spectroscopic data, and the absolute configurations of 1, 6, and 7 were established using circular dichroism (CD) analysis. Compound 1 showed Tyrosinase inhibitory activity (IC 50 2.2 mM).

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