2. Academic Validation
  3. Cytotoxic polyprenylated xanthones from the resin of Garcinia hanburyi

Cytotoxic polyprenylated xanthones from the resin of Garcinia hanburyi

  • J Nat Prod. 2009 Jan;72(1):117-24. doi: 10.1021/np800460b.
Si-Jia Tao 1,  Shu-Hong Guan,  Wei Wang,  Zhi-Qiang Lu,  Guang-Tong Chen,  Na Sha,  Qing-Xi Yue,  Xuan Liu,  De-An Guo
Affiliations

Affiliation

  • 1 Shanghai Research Center for Modernization of Traditional Chinese Medicine, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Zhangjiang, Shanghai 201203, People's Republic of China.
PMID: 19072548 DOI: 10.1021/np800460b
Abstract

Twelve new Xanthones (1-12), a pair of new Natural Products (13 and 14), and 18 known related compounds were isolated from the resin of Garcinia hanburyi. The structures of 1-14 were elucidated by detailed spectroscopic analyses. A cytotoxic assay of the isolated compounds revealed that, with the exception of 2, these compounds were active against the HeLa tumor cell line.

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