1. Natural Products
  2. Phenols
  3. Xanthones

Xanthones

Xanthones (39):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0328
    alpha-Mangostin 6147-11-1 99.64%
    alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a Ki of 2.85 μM.
    alpha-Mangostin
  • HY-N0290
    Mangiferin 4773-96-0 99.98%
    Mangiferin is a Nrf2 activator. Mangiferin suppresses nuclear translocation of the NF-κB subunits p65 and p50. Mangiferin exhibits antioxidant, antidiabetic, antihyperuricemic, antiviral, anticancer and antiinflammatory activities.
    Mangiferin
  • HY-N1957
    Gamma-Mangostin 31271-07-5 99.90%
    Gamma-Mangostin is a novel competitive 5-hydroxytryptamine 2A (5-HT2A) receptors antagonist, purified from the fruit hull of the medicinal plant Garcinia mangostana. Gamma-Mangostin is a inhibitor of Transthyretin (TTR) fibrillization, it binds to the thyroxine (T4)-binding sites and stabilized the TTR tetramer. Gamma-Mangostin inhibits [3H] spiperone binding to cultured rat aortic myocytes (IC50=3.5 nM) and reduces The perfusion pressure response of rat coronary artery to 5-HT2A (IC50=0.32 µM) .
    Gamma-Mangostin
  • HY-N6953
    Garcinone D 107390-08-9 98.19%
    Garcinone D, a natural xanthone from mangosteen, promotes the proliferation of C17.2 neural stem cell. Garcinone D increases the protein levels of phosphorylated signal transducer and activator of transcription 3 (p-STAT3), Cyclin D1 and nuclear factor erythroid 2-related factor (Nrf2), heme oxygenase-1 (HO-1) in concentration- and time- dependent manners.
    Garcinone D
  • HY-N0126
    Xanthone 90-47-1 99.66%
    Xanthone is isolated from Mangosteen and is known to control cell division and growth, apoptosis, inflammation, and metastasis in different stages of carcinogenesis. Xanthone has anti-oxidant, anti-tumor, anti-allergic, anti-inflammatory, anti-bacterial, anti-fungal, and anti-viral activities.
    Xanthone
  • HY-N10235
    Tajixanthone 35660-48-1
    Tajixanthone is the fungus metabolite from Aspergillus variecolor.
    Tajixanthone
  • HY-N9480
    Vinaxanthone 133293-89-7
    Vinaxanthone (SM-345431) is a potent and selective semaphorin3A inhibitor. Vinaxanthone exhibits semaphorin3A inhibiting activity with an IC50 of 0.1-0.2 μM. Vinaxanthone shows selective inhibitory activity against phospholipase C (PLC) from rat brain, mutine colon 26 Adenocarcinoma and murine fibroblasts NIH3T3 with IC50s being 5.4, 9.3 and 44 μM, respectively.
    Vinaxanthone
  • HY-N0941
    beta-Mangostin 20931-37-7 99.74%
    beta-Mangostin (β-Mangostin) is a xanthone compound present in Cratoxylum arborescens, with antibacterial and antimalarial activities. beta-Mangostin exhibits antimycobacterial activity against Mycobacterium tuberculosis with an MIC of 6.25 μg/mL. beta-Mangostin possesses in vitro antimalarial activity against Plasmodium falciparum, with an IC50 of 3.00 μg/mL. beta-Mangostin has potent anticancer activity against various cancers (such as hepatocellular carcinoma, leukaemic).
    beta-Mangostin
  • HY-N6954
    Garcinone C 76996-27-5 99.66%
    Garcinone C, a xanthone derivative, is a natural compound extracted from Garcinia oblongifolia Champ that is used as an anti-inflammatory, astringency and granulation-promoting medicine, and has potential cytotoxic effects on certain cancers. Garcinone C stimulates the expression levels of ATR and 4E-BP1, while efficiently inhibiting the expression levels of cyclin B1, cyclin D1, cyclin E2, cdc2, Stat3 and CDK7. Garcinone C significantly inhibits cell viability of the human Nasopharyngeal carcinoma (NPC) cell lines CNE1, CNE2, HK1 and HONE1 in a time‑ and dose‑dependent manner.
    Garcinone C
  • HY-N0772
    Isomangiferin 24699-16-9 99.82%
    Isomangiferin, a natural product, is reported to have antiviral activity.
    Isomangiferin
  • HY-N2050
    1,3,5,8-Tetrahydroxyxanthone 2980-32-7 99.34%
    1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) is a natural xanthone extracted from Gentianella acuta. 1,3,5,8-Tetrahydroxyxanthone has antispasmodic effect and anti-inflammatory activity.
    1,3,5,8-Tetrahydroxyxanthone
  • HY-N6725
    Sterigmatocystine 10048-13-2 ≥98.0%
    Sterigmatocystine is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor. Sterigmatocystine, a inhibitor of G1 Phase and DNA synthesis, is used to inhibit p21 activity. Sterigmatocystine has teratogenic, and carcinogenic effects in animals.
    Sterigmatocystine
  • HY-N2192
    Swertianolin 23445-00-3 99.54%
    Swertianolin, a xanthone isolated from Gentianella Acuta, inhibits acetylcholinesterase (AChE). Swertianolin also exhibits anti-HBV and anti-bacterial activity.
    Swertianolin
  • HY-N6038
    Gartanin 33390-42-0
    Gartanin is a natural xanthone of mangosteen, with antioxidant, anti-inflammatory, antifungal, neuroprotective and antineoplastic properties. Gartanin induces cell cycle arrest and autophagy and suppresses migration in human glioma cells.
    Gartanin
  • HY-N6617
    Norswertianolin 54954-12-0 99.27%
    Norswertianolin acts as a CSE activator and is isolated from G. acuta. Norswertianolin may be a potential agent for cardiovascular diseases.
    Norswertianolin
  • HY-N0723
    Neomangiferin 64809-67-2 99.87%
    Neomangiferin is a natural C-glucosyl xanthone isolated from m the dried rhizome of Anemarrhena asphodeloides. Neomangiferin has significant therapeutic effects on high-fat diet-induced nonalcoholic fatty liver disease (NAFLD) in rats.
    Neomangiferin
  • HY-N2159
    Lancerin 81991-99-3 99.69%
    Lancerin, isolated from the root bark of Cudraniu cochinchinensis, possesses anti-lipid peroxidation.
    Lancerin
  • HY-N1407
    Polygalaxanthone III 162857-78-5 99.76%
    Polygalaxanthone III is extracted from polygala tenuifolia wild, has inhibitory effect towards CYP450 enzyme. Polygalaxanthone III inhibits chlorzoxazone 6-hydroxylation catalyzed by CYP2E1 with an IC50 of 50.56 μM.
    Polygalaxanthone III
  • HY-N8088
    Neolancerin 117221-65-5
    Neolancerin is a natural product with weak cytotoxic activity against HL-60 cells.
    Neolancerin
  • HY-N6803
    Polygalaxanthone XI 857859-82-6
    Polygalaxanthone XI, a xanthone glycoside isolated from the cortexes of Polygala tenuifolia, can be used in the study of expectorant, and tranquilizing agent.
    Polygalaxanthone XI