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  2. 1,3,5,8-Tetrahydroxyxanthone

1,3,5,8-Tetrahydroxyxanthone (Synonyms: Desmethylbellidifolin)

Cat. No.: HY-N2050
Handling Instructions

1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) is a natural xanthone extracted from Gentianella acuta. 1,3,5,8-Tetrahydroxyxanthone has antispasmodic effect and anti-inflammatory activity.

For research use only. We do not sell to patients.

1,3,5,8-Tetrahydroxyxanthone Chemical Structure

1,3,5,8-Tetrahydroxyxanthone Chemical Structure

CAS No. : 2980-32-7

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Description

1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) is a natural xanthone extracted from Gentianella acuta. 1,3,5,8-Tetrahydroxyxanthone has antispasmodic effect and anti-inflammatory activity[1].

In Vitro

1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) attenuates lipopolysaccharide-induced nitric oxide release and proinflammatory cytokine expression in RAW264.7 cells[1].

In Vivo

1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin; orally; 5, 10, 20 mg/kg; 12 days) can inhibit trinitrobenzenesulfonic acid (TNBS)-induced ulcerative colitis (UC), reducing inflammatory response and alleviate colon muscle spasm[1].

Molecular Weight

260.20

Formula

C₁₃H₈O₆

CAS No.

2980-32-7

SMILES

O=C1C2=C(OC3=C1C(O)=CC=C3O)C=C(O)C=C2O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

1,3,5,8-TetrahydroxyxanthoneDesmethylbellidifolinOthersXanthoneantispasmodicanti-inflammatoryulcerativecolitiscolonmusclespasmInhibitorinhibitorinhibit

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