1. JAK/STAT Signaling
    Stem Cell/Wnt
    NF-κB
    Metabolic Enzyme/Protease
    Immunology/Inflammation
  2. STAT
    Keap1-Nrf2
    Reactive Oxygen Species
  3. Garcinone D

Garcinone D 

Cat. No.: HY-N6953 Purity: 98.18%
Handling Instructions

Garcinone D, a natural xanthone from mangosteen, promotes the proliferation of C17.2 neural stem cell. Garcinone D increases the protein levels of phosphorylated signal transducer and activator of transcription 3 (p-STAT3), Cyclin D1 and nuclear factor erythroid 2-related factor (Nrf2), heme oxygenase-1 (HO-1) in concentration- and time- dependent manners.

For research use only. We do not sell to patients.

Garcinone D Chemical Structure

Garcinone D Chemical Structure

CAS No. : 107390-08-9

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Description

Garcinone D, a natural xanthone from mangosteen, promotes the proliferation of C17.2 neural stem cell. Garcinone D increases the protein levels of phosphorylated signal transducer and activator of transcription 3 (p-STAT3), Cyclin D1 and nuclear factor erythroid 2-related factor (Nrf2), heme oxygenase-1 (HO-1) in concentration- and time- dependent manners[1].

IC50 & Target[1]

p-STAT3

 

Molecular Weight

428.47

Formula

C₂₄H₂₈O₇

CAS No.

107390-08-9

SMILES

CC(C)(O)CCC1=C(OC)C(O)=CC(OC2=CC(O)=C(C/C=C(C)/C)C(O)=C23)=C1C3=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

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Garcinone D
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