529-49-7
529-49-7
Chemical Structure
Gentisein
Synonym(s): NSC 329491; 1,3,7-Trihydroxyxanthone
- CAS No.: 529-49-7
- Formula:C13H8O5
- Molecular Weight:244.20
IUPAC Name: 1,3,7-trihydroxy-9H-xanthen-9-one
InChIKey: JJUNZBRHHGLJQW-UHFFFAOYSA-N
SMILES: O=C1C2=C(C=C(C=C2O)O)OC3=C1C=C(C=C3)O
Biological Activity: Gentisein (NSC 329491) is a metabolite of Mangiferin (HY-N0290) that inhibits the serotonin transporter (5-HT uptake system). Gentisein suppresses serotonin uptake and can be used in studies related to depression[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Gentisein | 98.07% | Gentisein (NSC 329491) is a metabolite of Mangiferin (HY-N0290) that inhibits the serotonin transporter (5-HT uptake system). Gentisein suppresses serotonin uptake and can be used in studies related to depression. | ||||||||||||||||||||
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Gentisein (Standard) | ≥98% | Gentisein (Standard) (NSC 329491 (Standard); 1,3,7-Trihydroxyxanthone (Standard)) is the analytical standard of Gentisein (HY-118166). This product is intended for research and analytical applications. Gentisein (NSC 329491) is a metabolite of Mangiferin (HY-N0290) that inhibits the serotonin transporter (5-HT uptake system). Gentisein suppresses serotonin uptake and can be used in studies related to depression. | ||||||||||||||||||||
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References
- [1]. Wang H, et al. Identification and determination of four metabolites of mangiferin in rat urine. Journal of pharmaceutical and biomedical analysis. 2007 Dec 21;45(5):793-8. [Content Brief]
- [2]. Zheleva-Dimitrova D, et al. Simultaneous determination of benzophenones and gentisein in Hypericum annulatum Moris by high-performance liquid chromatography. Phytochemical analysis : PCA. 2007;18(1):1-6.
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[3]. Tzankova V, et al. Inhibition of 5‑HT uptake by some constituents of Hypericum annulatum in rat brain in vitro. Pharmacologyonline. 2010;2:142‑150.
