529-49-7
529-49-7
Chemical Structure
Gentisein
Synonym(s): NSC 329491; 1,3,7-Trihydroxyxanthone
- CAS No.: 529-49-7
- Formula:C13H8O5
- Molecular Weight:244.20
IUPAC Name: 1,3,7-trihydroxy-9H-xanthen-9-one
InChIKey: JJUNZBRHHGLJQW-UHFFFAOYSA-N
SMILES: O=C1C2=C(C=C(C=C2O)O)OC3=C1C=C(C=C3)O
Biological Activity: Gentisein (NSC 329491), the major metabolite of Mangiferin, shows the most potent serotonin uptake inhibition with an IC50 value of 4.7 µM[1][2].
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Gentisein | 98.07% | Gentisein (NSC 329491), the major metabolite of Mangiferin, shows the most potent serotonin uptake inhibition with an IC50 value of 4.7 µM. | ||||||||||||||||||||
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Gentisein (Standard) | ≥98% | Gentisein (Standard) is the analytical standard of Gentisein. This product is intended for research and analytical applications. Gentisein (NSC 329491), the major metabolite of Mangiferin, shows the most potent serotonin uptake inhibition with an IC50 value of 4.7 µM. | ||||||||||||||||||||
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References
- [1]. Wang H, et al. Identification and determination of four metabolites of mangiferin in rat urine. J Pharm Biomed Anal. 2007;45(5):793-798. [Content Brief]
- [2]. Tzankova, Virginia et al. (2010). Inhibition of 5-HT uptake by some constituents of Hypericum annulatum in rat brain in vitro. Pharmacologyonline. 2.
Keywords
