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Cat. No.: HY-N13835

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2,6-Dihydroxyxanthone

2,6-Dihydroxyxanthone is a natural xanthone.

For research use only. We do not sell to patients.

CAS No.: 838-11-9
Formula: C₁₃H₈O₄
Molecular Weight:228.20

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

2,6-Dihydroxyxanthone Chemical Structure

CAS No.: 838-11-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

2,6-Dihydroxyxanthone is a natural xanthone.

Cellular Effect

Cell Line	Type	Value	Description	References
COLO 320	IC₅₀	31.5 μM Compound: 3-20	Antiproliferative activity against human COLO320 cells after 48 hrs by CCK8 assay Antiproliferative activity against human COLO320 cells after 48 hrs by CCK8 assay	[PMID: 28376372]
HepG2	IC₅₀	52.2 μM Compound: 3-20	Antiproliferative activity against human HepG2 cells after 48 hrs by CCK8 assay Antiproliferative activity against human HepG2 cells after 48 hrs by CCK8 assay	[PMID: 28376372]
HSC-T6	IC₅₀	>30 μM Compound: 7	Antiproliferative activity against rat HSC-T6 cells assessed as reduction in cell viability Antiproliferative activity against rat HSC-T6 cells assessed as reduction in cell viability	[PMID: 25322455]
K562	IC₅₀	88.9 μM Compound: 3-20	Antiproliferative activity against human K562 cells after 48 hrs by CCK8 assay Antiproliferative activity against human K562 cells after 48 hrs by CCK8 assay	[PMID: 28376372]
MCF7	IC₅₀	92.4 μM Compound: 3-20	Antiproliferative activity against human MCF7 cells after 48 hrs by CCK8 assay Antiproliferative activity against human MCF7 cells after 48 hrs by CCK8 assay	[PMID: 28376372]
MDA-MB-231	IC₅₀	32.4 μM Compound: 3-20	Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by CCK8 assay Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by CCK8 assay	[PMID: 28376372]

In Vitro

2,6-Dihydroxyxanthone (Compound 11) exhibits preferential cytotoxicity against PANC-1 human pancreatic cancer cells in nutrient-deprived medium (PC₅₀ = 45.2 μM)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 838-11-9
Molecular Weight 228.20
Formula C₁₃H₈O₄
SMILES

O=C1C2=CC=C(C=C2OC3=CC=C(C=C13)O)O
Structure Classification
- Phenols
- Xanthones
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Omar AM, et al. Benzophenones from Betula alnoides with Antiausterity Activities against the PANC-1 Human Pancreatic Cancer Cell Line. J Nat Prod. 2021 May 28;84(5):1607-1616. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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