2. Academic Validation
  3. Cathepsin K: a therapeutic target for bone diseases

Cathepsin K: a therapeutic target for bone diseases

  • Biochem Biophys Res Commun. 2009 Mar 20;380(4):721-3. doi: 10.1016/j.bbrc.2009.01.139.
Qingxiao Zhao 1,  Yanping Jia,  Yongtao Xiao
Affiliations

Affiliation

  • 1 College of Chemical Engineering, Northeast Dianli University, Jilin, PR China.
PMID: 19338743 DOI: 10.1016/j.bbrc.2009.01.139
Abstract

Cathepsin K is a member of the papain family of cysteine proteases and is highly expressed in osteoclasts that mediate bone resorption. In this review, some of the known features of Cathepsin K such as structure, function in bone resorption, gene regulation and its roles in physiological or pathophysiological processes are highlighted.

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