2. Academic Validation
  3. Iridoids and sesquiterpenoids from the roots of Valeriana officinalis

Iridoids and sesquiterpenoids from the roots of Valeriana officinalis

  • J Nat Prod. 2009 Sep;72(9):1682-5. doi: 10.1021/np9003382.
Peng-Cheng Wang 1,  Jiang-Miao Hu,  Xin-Hui Ran,  Zhong-Quan Chen,  He-Zhong Jiang,  Yu-Qing Liu,  Jun Zhou,  You-Xing Zhao
Affiliations

Affiliation

  • 1 State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, People's Republic of China.
PMID: 19691292 DOI: 10.1021/np9003382
Abstract

Two new Iridoids, volvaltrates A and B (1 and 2), and three new sesquiterpenoids, E-(-)-3beta,4beta-epoxyvalerenal (3), E-(-)-3beta,4beta-epoxyvalerenyl acetate (4), and mononorvalerenone (5), together with five known Iridoids and two known sesquiterpenoids were isolated from the roots of Valeriana officinalis. The structures and relative configurations of 1-5 were elucidated by spectroscopic evidence. Compound 1 was an unusual iridoid with an oxygen bridge connecting C-3 and C-10, forming a cage-like structure, and compound 5 was a mononorsesquiterpenoid.

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