Volvaltrate B
Volvaltrate B is an anticancer agent, iridoid, can be obtained from the root of valerian (Valeriana officinalis). Volvaltrate B is effective against ovarian tumors in female mice. Volvaltrate B has the potential to study cancer.
For research use only. We do not sell to patients.
- CAS No.: 1181224-13-4
- Formula: C27H41ClO11
- Molecular Weight:577.06
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
8.5 μM
Compound: 6
|
Cytotoxicity against human A549 cells after 24 hrs by MTT assay
Cytotoxicity against human A549 cells after 24 hrs by MTT assay
|
[PMID: 20853876] |
| Bel-7402 | IC50 |
6.1 μM
Compound: 6
|
Cytotoxicity against human Bel7402 cells after 24 hrs by MTT assay
Cytotoxicity against human Bel7402 cells after 24 hrs by MTT assay
|
[PMID: 20853876] |
| HCT-8 | IC50 |
3.2 μM
Compound: 6
|
Cytotoxicity against human HCT8 cells after 24 hrs by MTT assay
Cytotoxicity against human HCT8 cells after 24 hrs by MTT assay
|
[PMID: 20853876] |
| PC-3M | IC50 |
2 μM
Compound: 6
|
Cytotoxicity against human PC3M cells after 24 hrs by MTT assay
Cytotoxicity against human PC3M cells after 24 hrs by MTT assay
|
[PMID: 20853876] |
Chemical Information
-
CAS No. 1181224-13-4
-
Molecular Weight 577.06
-
Formula C27H41ClO11
-
SMILES
CC(C)[C@@H](OC(CC(C)C)=O)C(OCC1=CO[C@@H](OC(CC(C)C)=O)[C@@]2([H])[C@]1(O)C[C@H](OC(C)=O)[C@@]2(CCl)O)=O
-
Structure Classification
-
Initial Source
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Tan YZ, et al. Iridoids from Valeriana jatamansi induce autophagy-associated cell death via the PDK1/Akt/mTOR pathway in HCT116 human colorectal carcinoma cells. Bioorg Chem. 2019 Jun;87:136-141. [Content Brief]
[2]. Wang PC, et al. Iridoids and sesquiterpenoids from the roots of Valeriana officinalis. J Nat Prod. 2009 Sep;72(9):1682-5. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Volvaltrate B Related Classifications
HY-133800 Related Classifications
Powered by Bioz