- Natural Products
- Plants
- Valerianaceae
- Valeriana officinalis Linn.
Valeriana officinalis Linn.
Alias: Valerian
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Valeriana officinalis Linn. (19)
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- Formula: C24H32O10
- Molecular Weight: 480.50
Acevaltrate inhibits the Na+/K+-ATPase activity in the rat kidney and brain hemispheres with IC50s of 22.8 μM and 42.3 μM, respectively.
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- Formula: C17H24O4
- Molecular Weight: 292.37
Acetoxyvalerenic acid is a natural compound that could be found in valerian.
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- Formula: C12H10O4
- Molecular Weight: 218.21
Baldrinal is derived from the extracts of valerian rhizomes and roots, inhibits autonomic activity, and has anti-inflammatory effects.
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- Formula: C22H32O8
- Molecular Weight: 424.48
Didrovaltrate (Didrovaltratum) is an L-type calcium channel blocker, ROS scavenger, autophagy enhancer, and lipid accumulation inhibitor. Didrovaltrate blocks L-type calcium currents in a concentration-dependent manner, shifts the current-voltage curve upward, modulates steady-state inactivation kinetics, and inhibits the nuclear translocation of glucocorticoid receptors. Didrovaltrate reduces ROS levels, downregulates the expression of muscle atrophy-related genes, enhances autophagy via lipophagy, and decreases Oleic acid-induced lipid accumulation. Didrovaltrate exhibits cytotoxic activity against cancer cells. Didrovaltrate can be used in research related to skeletal muscle atrophy, non-alcoholic fatty liver disease, breast cancer, lung cancer, gastric cancer, and prostate cancer.
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- Formula: C15H26O2
- Molecular Weight: 238.37
Bornyval is a derivative preparation of valerian (Baldrian).
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- Formula: C15H22O3
- Molecular Weight: 250.33
Hydroxyvalerenic acid (Standard) is the analytical standard of Hydroxyvalerenic acid. This product is intended for research and analytical applications. Hydroxyvalerenic acid is isolated from Verbena officinalis, has a low toxicity with IC50 values of 123 and 165 μM against GLC4 and COLO 320 cells, respectively.
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- Formula: C17H24O4
- Molecular Weight: 292.37
Acetoxyvalerenic acid (Standard) is the analytical standard of Acetoxyvalerenic acid. This product is intended for research and analytical applications. Acetoxyvalerenic acid is a natural compound that could be found in valerian.
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- Formula: C17H24O3
- Molecular Weight: 276.37
Volvalerenal E is an active product that can be isolated from a chloroform extract of the roots of Valeriana officinalis var. latifolia..
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- Formula: C15H22O
- Molecular Weight: 218.33
Kissoone A (compound 1) is a three-membered ring sesquiterpene isolated from valerian root.
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- Formula: C17H24O3
- Molecular Weight: 276.37
Kissoone C (compound 3) is a three-membered ring sesquiterpene isolated from valerian root. Kissoone C can enhance the activity of nerve growth factor (NGF)-mediated neurite outgrowth in PC12D cells.
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- Formula: C15H24O2
- Molecular Weight: 236.35
9-Oxonerolidol is a farnesane-type sesquiterpenoid with anti-pathogens activity. 9-Oxonerolidol can be isolated from Chiliadenus lopadusanus. 9-Oxonerolidol acts as a post-infectional inhibitor from plants, and inhibits Gram+ and Gram? bacteria resistant to the antibiotic.
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- Formula: C27H41ClO11
- Molecular Weight: 577.06
Volvaltrate B is an anticancer agent, iridoid, can be obtained from the root of valerian (Valeriana officinalis). Volvaltrate B is effective against ovarian tumors in female mice. Volvaltrate B has the potential to study cancer.
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- Formula: C15H22O
- Molecular Weight: 218.33
(-)-Isobicyclogermacrenal is a natural sesquiterpene hydrocarbon.
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- Formula: C27H40O11
- Molecular Weight: 540.60
IVHD-valtrate, an active Valeriana jatamansi derivative, is against human ovarian cancer cells in vitro and in vivo. IVHD-valtrate induces cancer cells apoptosis and arrests the ovarian cancer cells in the G2/M phase. IVHD-valtrate has the potential to be a novel chemotherapeutic agent for the human ovarian cancer research.
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- Formula: C15H16O4
- Molecular Weight: 260.29
Homobaldrinal is a decomposition product of Valepotriate (HY-N0718). Homobaldrinal exhibits genotoxic activity in the Salmonella/microsome test.
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- Formula: C24H32O10
- Molecular Weight: 480.50
Acevaltrate inhibits the Na+/K+-ATPase activity in the rat kidney and brain hemispheres with IC50s of 22.8 μM and 42.3 μM, respectively.
August 31
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