Valeriana officinalis Linn. Extract

Acevaltrate inhibits the Na⁺/K⁺-ATPase activity in the rat kidney and brain hemispheres with IC₅₀s of 22.8 μM and 42.3 μM, respectively.

Acetoxyvalerenic acid is a natural compound that could be found in valerian.

Hydroxyvalerenic acid is isolated from Verbena officinalis, has a low toxicity with IC₅₀ values of 123 and 165 μM against GLC4 and COLO 320 cells, respectively.

Baldrinal is derived from the extracts of valerian rhizomes and roots, inhibits autonomic activity, and has anti-inflammatory effects.

Didrovaltrate (Didrovaltratum) is an L-type calcium channel blocker, ROS scavenger, autophagy enhancer, and lipid accumulation inhibitor. Didrovaltrate blocks L-type calcium currents in a concentration-dependent manner, shifts the current-voltage curve upward, modulates steady-state inactivation kinetics, and inhibits the nuclear translocation of glucocorticoid receptors. Didrovaltrate reduces ROS levels, downregulates the expression of muscle atrophy-related genes, enhances autophagy via lipophagy, and decreases Oleic acid-induced lipid accumulation. Didrovaltrate exhibits cytotoxic activity against cancer cells. Didrovaltrate can be used in research related to skeletal muscle atrophy, non-alcoholic fatty liver disease, breast cancer, lung cancer, gastric cancer, and prostate cancer.

Valeriana officinalis polysaccharide is a polysaccharide derived from Valeriana officinalis.

Bornyval is a derivative preparation of valerian (Baldrian).

Valerenal (Nardal) is a sesquiterpene found in Valeriana officinalis root oil. Valerian root can be used as an herbal sedative which is helpful in the treatment of insomnia.

Hydroxyvalerenic acid (Standard) is the analytical standard of Hydroxyvalerenic acid. This product is intended for research and analytical applications. Hydroxyvalerenic acid is isolated from Verbena officinalis, has a low toxicity with IC50 values of 123 and 165 μM against GLC4 and COLO 320 cells, respectively.

Acetoxyvalerenic acid (Standard) is the analytical standard of Acetoxyvalerenic acid. This product is intended for research and analytical applications. Acetoxyvalerenic acid is a natural compound that could be found in valerian.

Volvalerenal E is an active product that can be isolated from a chloroform extract of the roots of Valeriana officinalis var. latifolia..

Kissoone A (compound 1) is a three-membered ring sesquiterpene isolated from valerian root.

Kissoone C (compound 3) is a three-membered ring sesquiterpene isolated from valerian root. Kissoone C can enhance the activity of nerve growth factor (NGF)-mediated neurite outgrowth in PC12D cells.

Drimenol is a drimane-type sesquiterpene that can be isolated from Valerian plant.

9-Oxonerolidol is a farnesane-type sesquiterpenoid with anti-pathogens activity. 9-Oxonerolidol can be isolated from Chiliadenus lopadusanus. 9-Oxonerolidol acts as a post-infectional inhibitor from plants, and inhibits Gram+ and Gram? bacteria resistant to the antibiotic.

Volvaltrate B is an anticancer agent, iridoid, can be obtained from the root of valerian (Valeriana officinalis). Volvaltrate B is effective against ovarian tumors in female mice. Volvaltrate B has the potential to study cancer.

(-)-Isobicyclogermacrenal is a natural sesquiterpene hydrocarbon.

IVHD-valtrate, an active Valeriana jatamansi derivative, is against human ovarian cancer cells in vitro and in vivo. IVHD-valtrate induces cancer cells apoptosis and arrests the ovarian cancer cells in the G2/M phase. IVHD-valtrate has the potential to be a novel chemotherapeutic agent for the human ovarian cancer research.

Homobaldrinal is a decomposition product of Valepotriate (HY-N0718). Homobaldrinal exhibits genotoxic activity in the Salmonella/microsome test.

Acevaltrate inhibits the Na+/K+-ATPase activity in the rat kidney and brain hemispheres with IC50s of 22.8 μM and 42.3 μM, respectively.