2. Academic Validation
  3. Recent developments in chitosanase research and its biotechnological applications: a review

Recent developments in chitosanase research and its biotechnological applications: a review

  • Food Chem. 2014 May 1:150:392-9. doi: 10.1016/j.foodchem.2013.10.083.
Nidheesh Thadathil 1,  Suresh Puthanveetil Velappan 2
Affiliations

Affiliations

  • 1 Academy of Scientific and Innovative Research, CSIR-Central Food Technological Research Institute, Mysore 570020, India; Department of Meat and Marine Sciences, CSIR-Central Food Technological Research Institute, Mysore 570020, India. Electronic address: [email protected].
  • 2 Academy of Scientific and Innovative Research, CSIR-Central Food Technological Research Institute, Mysore 570020, India; Department of Meat and Marine Sciences, CSIR-Central Food Technological Research Institute, Mysore 570020, India. Electronic address: [email protected].
PMID: 24360467 DOI: 10.1016/j.foodchem.2013.10.083
Abstract

Chitosanases (EC 3.2.1.132) are glycosyl hydrolases that catalyse the endohydrolysis of β-1,4-glycosidic bonds of partially acetylated chitosan to release chitosan oligosaccharides (COS). Chitosanases are isolated, purified and characterised from different sources mainly from bacteria and fungi. Chitosanases have received much attention due to their wide range of applications including the preparation of bioactive COS and Fungal protoplasts, as biocontrol agent against pathogenic fungi and insects, the bioconversion of chitinous bio waste associated with seafood processing, etc. Bioactive COS produced by the enzymatic hydrolysis of chitosan have finds numerous health benefits as well as other biological activities. This review summarizes the recent advances in chitosanases research, the Enzyme production processes, characterization, genetic improvement and their applications.

Keywords

Chitosan; Chitosan oligosaccharides; Chitosanase; N-Acetyl-d-glucosamine; d-Glucosamine.

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