2. Academic Validation
  3. Amplified effect of surface charge on cell adhesion by nanostructures

Amplified effect of surface charge on cell adhesion by nanostructures

  • Nanoscale. 2016 Jul 7;8(25):12540-3. doi: 10.1039/c6nr00649c.
Li-Ping Xu 1,  Jingxin Meng,  Shuaitao Zhang,  Xinlei Ma,  Shutao Wang
Affiliations

Affiliation

  • 1 Research Center for Bioengineering & Sensing Technology, University of Science and Technology Beijing, Beijing, 100083, P. R. China.
PMID: 27150434 DOI: 10.1039/c6nr00649c
Abstract

Nano-biointerfaces with varied surface charge can be readily fabricated by integrating a template-based process with maleimide-thiol coupling chemistry. Significantly, nanostructures are employed for amplifying the effect of surface charge on cell adhesion, as revealed by the cell-adhesion performance, cell morphology and corresponding cytoskeletal organization. This study may provide a promising strategy for developing new biomedical Materials with tailored cell adhesion for tissue implantation and regeneration.

Figures
Products