2. Academic Validation
  3. New Acetophenone Derivatives from Acronychia oligophlebia and Their Anti-inflammatory and Antioxidant Activities

New Acetophenone Derivatives from Acronychia oligophlebia and Their Anti-inflammatory and Antioxidant Activities

  • Chem Biodivers. 2018 May;15(5):e18000080. doi: 10.1002/cbdv.201800080.
Neng-Hua Chen 1 2,  Wen Li 3,  Yuan-Lin Zhong 1 2,  Qian-Wen Niu 1 2,  Ying-Ying Li 1 2,  Yu-Bo Zhang 1 2,  Man-Mei Li 1 2,  Yao-Lan Li 1 2,  Guo-Cai Wang 1 2
Affiliations

Affiliations

  • 1 Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou, 510632, P. R. China.
  • 2 Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou, 510632, P. R. China.
  • 3 Guangdong Saskatchewan Oilseed Joint Laboratory, Guangdong Engineering Technology Research Center for Oils and Fats Biorefinery, Department of Food Science and Engineering, Jinan University, Guangzhou, 510632, China.
PMID: 29624846 DOI: 10.1002/cbdv.201800080
Abstract

Seven new acetophenone derivatives (acroliones A - G, 1 - 7) and three known ones (8 - 10) were isolated from the leaves of Acronychia oligophlebia. Their structures were elucidated based on extensive spectroscopic analyses (IR, UV, HR-ESI-MS, 1D- and 2D-NMR), X-ray diffraction and comparison with literature data. The anti-inflammatory and antioxidant activities of all isolates were evaluated.

Keywords

Acronychia oligophlebia; acetophenone derivatives; anti-inflammatory activity; antioxidant activity; structural elucidation.

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