2. Academic Validation
  3. Highly potent and selective ligands for histamine H3-receptors

Highly potent and selective ligands for histamine H3-receptors

  • Nature. 1987 May 14-20;327(6118):117-23. doi: 10.1038/327117a0.
J M Arrang,  M Garbarg,  J C Lancelot,  J M Lecomte,  H Pollard,  M Robba,  W Schunack,  J C Schwartz
PMID: 3033516 DOI: 10.1038/327117a0
Abstract

New drugs selective for histamine H3-receptors can be used to establish that these receptors are involved in the feedback control of histamine synthesis and release, and to demonstrate their distribution in the brain and peripheral tissues. These drugs provide new tools for affecting physiological and possibly pathological conditions in which histamine is involved.

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