2. Academic Validation
  3. A PSTAIRE-type cyclin-dependent kinase controls light responses in land plants

A PSTAIRE-type cyclin-dependent kinase controls light responses in land plants

  • Sci Adv. 2022 Jan 28;8(4):eabk2116. doi: 10.1126/sciadv.abk2116.
Liang Bao 1,  Natsumi Inoue 1,  Masaki Ishikawa 2 3,  Eiji Gotoh 4,  Ooi-Kock Teh 5,  Takeshi Higa 6,  Tomoro Morimoto 1,  Eggie Febrianto Ginanjar 1,  Hirofumi Harashima 7,  Natsumi Noda 8,  Masaaki Watahiki 8,  Yuji Hiwatashi 9,  Masami Sekine 10,  Mitsuyasu Hasebe 2 3,  Masamitsu Wada 6,  Tomomichi Fujita 8
Affiliations

Affiliations

  • 1 Graduate School of Life Science, Hokkaido University, Sapporo 060-0810, Japan.
  • 2 Division of Evolutionary Biology, National Institute for Basic Biology, Okazaki 444-8585, Japan.
  • 3 School of Life Science, SOKENDAI (The Graduate University for Advanced Studies), Okazaki 444-8585, Japan.
  • 4 Faculty of Agriculture, Kyushu University, Fukuoka 819-0395, Japan.
  • 5 Institute for the Advancement of Higher Education, Hokkaido University, Sapporo 060-0817, Japan.
  • 6 Faculty of Science, Kyushu University, Fukuoka 812-8581, Japan.
  • 7 Cell Function Research Team, RIKEN Centre for Sustainable Resource Science, Yokohama 230-0045, Japan.
  • 8 Faculty of Science, Hokkaido University, Sapporo 060-0810, Japan.
  • 9 School of Food Industrial Sciences, Miyagi University, Sendai 982-0215, Japan.
  • 10 Faculty of Bioresources and Environmental Sciences, Ishikawa Prefectural University, Nonoichi 921-8836, Japan.
PMID: 35089781 DOI: 10.1126/sciadv.abk2116
Abstract

LIGHT is a critical signal perceived by Plants to adapt their growth rate and direction. Although many signaling components have been studied, how Plants respond to constantly fluctuating LIGHT remains underexplored. Here, we showed that in the moss Physcomitrium (Physcomitrella) patens, the PSTAIRE-type cyclin-dependent kinase PpCDKA is dispensable for growth. Instead, PpCDKA and its homolog in Arabidopsis thaliana control light-induced tropisms and chloroplast movements by probably influencing the Cytoskeleton organization independently of the cell cycle. In addition, lower PpCDKA kinase activity was required to elicit LIGHT responses relative to cell cycle regulation. Thus, our study suggests that plant CDKAs may have been co-opted to control multiple LIGHT responses, and owing to the bistable switch properties of PSTAIRE-type CDKs, the noncanonical functions are widely conserved for eukaryotic environmental adaptation.

Figures
Products
  • Cat. No.
    Product Name
    Description
    Target
    Research Area
  • HY-10012
    99.85%, CDK1/2/9 Inhibitor
    CDK