1. Academic Validation
  2. Two new bibenzyls from Pleione grandiflora (Rolfe) Rolfe and their antioxidant activity

Two new bibenzyls from Pleione grandiflora (Rolfe) Rolfe and their antioxidant activity

  • Nat Prod Res. 2023 Jul-Aug;37(15):2486-2492. doi: 10.1080/14786419.2022.2050909.
Wei Li 1 Jia-Rui Fu 2 Li-Jun Zheng 3 Lin Ni 2 Jun-Qing Liu 2 Jun-Wen Zhai 1 Zhuang Zhou 4 Sha-Sha Wu 1
Affiliations

Affiliations

  • 1 College of Landscape Architecture, Fujian Agriculture and Forestry University, Fuzhou, P. R. China.
  • 2 Key Laboratory of Biopesticide and Chemical Biology, Ministry of Education, Fujian Agriculture and Forestry University, Fuzhou, P. R. China.
  • 3 Department of Pharmacy, Fujian Medical University Union Hospital, Fuzhou, P. R. China.
  • 4 Zhejiang Institute of Subtropical Crops, Zhejiang Academy of Agricultural Sciences, Wenzhou, P. R. China.
Abstract

Two new bibenzyls (1 and 2) were isolated from the pseudobulbs of Pleione grandiflora (Rolfe) Rolfe along with six known compounds, including isoarundinin I (3), isoarundinin II (4), bulbocodin D (5), batatasin III (6), 5,3'-dihydroxy- 4-(p-hydroxybenzyl)-3-methoxybibenzyl (7) and shancigusin F (8). Their structures were established on the basis of spectroscopic methods. These compounds showed potent DPPH free radical scavenging effects with IC50 values ranging from 49.72 ± 0.35 μM to 65.41 ± 0.49 μM.

Keywords

Orchidaceae; Pleione grandiflora (Rolfe) Rolfe; antioxidant; new bibenzyl compounds; pseudobulbs.

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