1. Academic Validation
  2. Advances and Prospects in the Treatment of Pancreatic Cancer

Advances and Prospects in the Treatment of Pancreatic Cancer

  • Int J Nanomedicine. 2023 Jul 19:18:3973-3988. doi: 10.2147/IJN.S413496.
Huaiyu Duan # 1 Li Li # 2 Shiming He 1
Affiliations

Affiliations

  • 1 School of Integrated Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei, People's Republic of China.
  • 2 Department of Hepatobiliary Pancreatic Oncology, Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, People's Republic of China.
  • # Contributed equally.
Abstract

Pancreatic Cancer is a highly malignant and incurable disease, characterized by its aggressive nature and high fatality rate. The most common type is pancreatic ductal adenocarcinoma (PDAC), which has poor prognosis and high mortality rate. Current treatments for pancreatic Cancer mainly encompass surgery, chemotherapy, radiotherapy, targeted therapy, and combination regimens. However, despite efforts to improve prognosis, and the 5-year survival rate for pancreatic Cancer remains very low. Therefore, it's urgent to explore novel therapeutic approaches. With the rapid development of therapeutic strategies in recent years, new ideas have been provided for treating pancreatic Cancer. This review expositions the advancements in nano drug delivery system, molecular targeted drugs, and photo-thermal treatment combined with nanotechnology for pancreatic Cancer. It comprehensively analyzes the prospects of combined drug delivery strategies for treating pancreatic Cancer, aiming at a deeper understanding of the existing drugs and therapeutic approaches, promoting the development of new therapeutic drugs, and attempting to enhance the therapeutic effect for patients with this disease.

Keywords

molecular targeted drugs; nano drug delivery system; pancreatic cancer; photo-thermal treatment.

Figures
Products
  • Cat. No.
    Product Name
    Description
    Target
    Research Area
  • HY-P992367
    Trop2 Targeting Antibody